In a retrospective study of 227 cases of esophagus atresia born in the southwest of England, the incidence was 0.34 per 1,000 births. Taking estimated dates of conception, there were no statistically significant yearly or monthly trends. There was a statistically significant winter excess of conceptions in the offspring of primigravidae but not multigravidae. Examination of the data for clustering, using a time interval analysis, failed to show an increased risk of a case occurring within 4 wk of a previous case. It is concluded that esophagus atresia is etiologically heterogeneous.
|Number of pages||4|
|Journal||British Journal of Preventive and Social Medicine|
|Publication status||Published - 1974|