Personality has been studied as a predictor variable in a range of occupational settings. The study reported is based on a systematic search and meta-analysis of the literature, using the "Big Five" personality framework. The results indicated that there was substantial variability in the effect of personality on workplace accidents, with evidence of situational moderators operating in most cases. However, one aspect of personality, low agreeableness, was found to be a valid and generalisable predictor of involvement in work accidents. The implications of the findings for future research are discussed. Although meta-analysis can be used to provide definite estimates of effect sizes, the limitations of such an approach are also considered. © 2007 International Association for Applied Psychology.