An expedient enzymatic route to isomeric 2-, 3- and 6-monodeoxy-monofluoro- maltose derivatives

K. Tantanarat; M. Rejzek; E. O'Neill; C. Ruzanski; L. Hill; S.A. Fairhurst; T. Limpaseni; R.A. Field

doi:10.1016/j.carres.2012.05.026

An expedient enzymatic route to isomeric 2-, 3- and 6-monodeoxy-monofluoro- maltose derivatives

K. Tantanarat
, M. Rejzek
, E. O'Neill
, C. Ruzanski
, L. Hill
, S.A. Fairhurst
, T. Limpaseni
, R.A. Field

Manchester Institute of Biotechnology

Research output: Contribution to journal › Article › peer-review

Abstract

2-Deoxy-2-fluoro-d-glucose, 3-deoxy-3-fluoro-d-glucose and 6-deoxy-6-fluoro-d-glucose were converted into the corresponding maltose derivatives using Arabidopsis thaliana DPE2-mediated trans-glycosylation reaction with glycogen acting as a glucosyl donor. 19F NMR spectroscopy proved to be a valuable tool for monitoring the progress of these reactions and to assess the nature of resulting oligomeric products.

Original language	Undefined
Pages (from-to)	12-18
Number of pages	7
Journal	Carbohydrate Research
DOIs	https://doi.org/10.1016/j.carres.2012.05.026
Publication status	Published - 2012

Research Beacons, Institutes and Platforms

Manchester Institute of Biotechnology

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10.1016/j.carres.2012.05.026

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title = "An expedient enzymatic route to isomeric 2-, 3- and 6-monodeoxy-monofluoro- maltose derivatives",

abstract = "2-Deoxy-2-fluoro-d-glucose, 3-deoxy-3-fluoro-d-glucose and 6-deoxy-6-fluoro-d-glucose were converted into the corresponding maltose derivatives using Arabidopsis thaliana DPE2-mediated trans-glycosylation reaction with glycogen acting as a glucosyl donor. 19F NMR spectroscopy proved to be a valuable tool for monitoring the progress of these reactions and to assess the nature of resulting oligomeric products.",

author = "K. Tantanarat and M. Rejzek and E. O'Neill and C. Ruzanski and L. Hill and S.A. Fairhurst and T. Limpaseni and R.A. Field",

year = "2012",

doi = "10.1016/j.carres.2012.05.026",

language = "Undefined",

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journal = "Carbohydrate Research",

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T1 - An expedient enzymatic route to isomeric 2-, 3- and 6-monodeoxy-monofluoro- maltose derivatives

AU - Tantanarat, K.

AU - Rejzek, M.

AU - O'Neill, E.

AU - Ruzanski, C.

AU - Hill, L.

AU - Fairhurst, S.A.

AU - Limpaseni, T.

AU - Field, R.A.

PY - 2012

Y1 - 2012

N2 - 2-Deoxy-2-fluoro-d-glucose, 3-deoxy-3-fluoro-d-glucose and 6-deoxy-6-fluoro-d-glucose were converted into the corresponding maltose derivatives using Arabidopsis thaliana DPE2-mediated trans-glycosylation reaction with glycogen acting as a glucosyl donor. 19F NMR spectroscopy proved to be a valuable tool for monitoring the progress of these reactions and to assess the nature of resulting oligomeric products.

AB - 2-Deoxy-2-fluoro-d-glucose, 3-deoxy-3-fluoro-d-glucose and 6-deoxy-6-fluoro-d-glucose were converted into the corresponding maltose derivatives using Arabidopsis thaliana DPE2-mediated trans-glycosylation reaction with glycogen acting as a glucosyl donor. 19F NMR spectroscopy proved to be a valuable tool for monitoring the progress of these reactions and to assess the nature of resulting oligomeric products.

UR - https://www.scopus.com/pages/publications/84865050325

U2 - 10.1016/j.carres.2012.05.026

DO - 10.1016/j.carres.2012.05.026

M3 - Article

SN - 0008-6215

SP - 12

EP - 18

JO - Carbohydrate Research

JF - Carbohydrate Research

ER -

An expedient enzymatic route to isomeric 2-, 3- and 6-monodeoxy-monofluoro- maltose derivatives

Abstract

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