An integrated biorefinery framework for the coproduction of biofuels and chemicals: Experimental analysis, detailed modelling, optimization and life cycle analysis

In this work, a novel integrated biorefinery framework is introduced. A 'cradle to grave' analysis is developed by adding novel steps into a basic biodiesel process involving the valorization of waste streams to value-added chemicals. Insights are given towards a new bioconversion route of glycerol to succinic acid. An unstructured model of batch experiments at different conditions is constructed. Experimental results at the bench scale are used to estimate kinetic parameters and to validate model predictions. The developed model is used in optimization studies to compute the best initial conditions for batch as well as the optimal feeding profiles for fed-batch processes to maximize succinic acid productivity. Finally, the above process is incorporated into a biorefinery scheme. Simulation and optimization in conjunction with life cycle analysis (LCA) is performed to simultaneously improve its sustainability and its economics. Copyright © 2010, AIDIC Servizi S.r.l.