TY - GEN
T1 - An integrative approach to cerebrovascular disease healthcarE
T2 - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
AU - Watton, Paul N.
AU - Frangi, Alejandro F
AU - Ventikos, Yiannis
PY - 2009
Y1 - 2009
N2 - One of the central themes in addressing vascular disease is connected with the behavior of the arterial wall; its response to stimuli, its remodeling, the growth or stabilization of lesions and the interaction with implants and drugs. For the case of cerebral aneurysms, we are presenting an effort to embed computational simulation models capable of handling such processes within an IT framework that combines imaging, modeling, genetics and clinical medicine in an integrative and comprehensive fashion. The @neurIST project aims at the development of an IT-enabled patient risk assessment and guidelines generation environment, capable of optimized decision support and treatment design. Within this framework, we present mechanobiological models of the vascular wall that account for the interaction of heamodynamics with vascular wall fiber and cell population and behavior.
AB - One of the central themes in addressing vascular disease is connected with the behavior of the arterial wall; its response to stimuli, its remodeling, the growth or stabilization of lesions and the interaction with implants and drugs. For the case of cerebral aneurysms, we are presenting an effort to embed computational simulation models capable of handling such processes within an IT framework that combines imaging, modeling, genetics and clinical medicine in an integrative and comprehensive fashion. The @neurIST project aims at the development of an IT-enabled patient risk assessment and guidelines generation environment, capable of optimized decision support and treatment design. Within this framework, we present mechanobiological models of the vascular wall that account for the interaction of heamodynamics with vascular wall fiber and cell population and behavior.
KW - Cerebral aneurysms
KW - Growth and Remodeling
KW - Healthcare
KW - Information technology
KW - Simulation
KW - Vascular disease
UR - http://www.scopus.com/inward/record.url?scp=70449368562&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2009.5193063
DO - 10.1109/ISBI.2009.5193063
M3 - Conference contribution
AN - SCOPUS:70449368562
SN - 9781424439324
T3 - Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
SP - 378
EP - 381
BT - Proceedings - 2009 IEEE International Symposium on Biomedical Imaging
Y2 - 28 June 2009 through 1 July 2009
ER -
