An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma: Final analysis and a validated prognostic scoring system

James Larkin; Michael P Brown; Ana M. Arance; Axel Hauschild; Paola Queirolo; Michele Del Vecchio; Paolo A.  Ascierto; Ivana Krajsova; Jacob Schachter; Bart Neyns; Claus Garbe; Vanna Chiarion Sileni; Mario Mandala; Helen Gogas; Enrique Espinosa; Geke A P Hospers; Paul Lorigan; Marta Nyakas; Alexander Guminski; Gabriela Liszkay; Piotr Rutkowski; Wilson H. Miller; Margarita Donica; Martina Makrutzki; Christian  Blank

doi:10.1016/j.ejca.2018.11.018

An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma: Final analysis and a validated prognostic scoring system

James Larkin
, Michael P Brown
, Ana M. Arance
, Axel Hauschild
, Paola Queirolo
, Michele Del Vecchio
, Paolo A. Ascierto
, Ivana Krajsova
, Jacob Schachter
, Bart Neyns
, Claus Garbe
, Vanna Chiarion Sileni
, Mario Mandala
, Helen Gogas
, Enrique Espinosa
, Geke A P Hospers
, Paul Lorigan
, Marta Nyakas
, Alexander Guminski
, Gabriela Liszkay

Piotr Rutkowski, Wilson H. Miller, Margarita Donica, Martina Makrutzki, Christian Blank

Division of Cancer Sciences (L5)

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	PMID: 30580112
Pages (from-to)	175-185
Journal	Eur. J. Cancer
Volume	107
Early online date	20 Dec 2018
DOIs	https://doi.org/10.1016/j.ejca.2018.11.018
Publication status	Published - 1 Jan 2019

Research Beacons, Institutes and Platforms

Manchester Cancer Research Centre

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ejca.2018.11.018

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Larkin, J., Brown, M. P., Arance, A. M., Hauschild, A., Queirolo, P., Del Vecchio, M., Ascierto, P. A., Krajsova, I., Schachter, J., Neyns, B., Garbe, C., Sileni, V. C., Mandala, M., Gogas, H., Espinosa, E., Hospers, G. A. P., Lorigan, P., Nyakas, M., Guminski, A., ... Blank, C. (2019). An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma: Final analysis and a validated prognostic scoring system. Eur. J. Cancer, 107, 175-185. Article PMID: 30580112 . https://doi.org/10.1016/j.ejca.2018.11.018

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title = "An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma: Final analysis and a validated prognostic scoring system",

author = "James Larkin and Brown, \{Michael P\} and Arance, \{Ana M.\} and Axel Hauschild and Paola Queirolo and \{Del Vecchio\}, Michele and Ascierto, \{Paolo A.\} and Ivana Krajsova and Jacob Schachter and Bart Neyns and Claus Garbe and Sileni, \{Vanna Chiarion\} and Mario Mandala and Helen Gogas and Enrique Espinosa and Hospers, \{Geke A P\} and Paul Lorigan and Marta Nyakas and Alexander Guminski and Gabriela Liszkay and Piotr Rutkowski and Miller, \{Wilson H.\} and Margarita Donica and Martina Makrutzki and Christian Blank",

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month = jan,

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doi = "10.1016/j.ejca.2018.11.018",

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Larkin, J, Brown, MP, Arance, AM, Hauschild, A, Queirolo, P, Del Vecchio, M, Ascierto, PA, Krajsova, I, Schachter, J, Neyns, B, Garbe, C, Sileni, VC, Mandala, M, Gogas, H, Espinosa, E, Hospers, GAP, Lorigan, P, Nyakas, M, Guminski, A, Liszkay, G, Rutkowski, P, Miller, WH, Donica, M, Makrutzki, M & Blank, C 2019, 'An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma: Final analysis and a validated prognostic scoring system', Eur. J. Cancer, vol. 107, PMID: 30580112 , pp. 175-185. https://doi.org/10.1016/j.ejca.2018.11.018

TY - JOUR

T1 - An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma

T2 - Final analysis and a validated prognostic scoring system

AU - Larkin, James

AU - Brown, Michael P

AU - Arance, Ana M.

AU - Hauschild, Axel

AU - Queirolo, Paola

AU - Del Vecchio, Michele

AU - Ascierto, Paolo A.

AU - Krajsova, Ivana

AU - Schachter, Jacob

AU - Neyns, Bart

AU - Garbe, Claus

AU - Sileni, Vanna Chiarion

AU - Mandala, Mario

AU - Gogas, Helen

AU - Espinosa, Enrique

AU - Hospers, Geke A P

AU - Lorigan, Paul

AU - Nyakas, Marta

AU - Guminski, Alexander

AU - Liszkay, Gabriela

AU - Rutkowski, Piotr

AU - Miller, Wilson H.

AU - Donica, Margarita

AU - Makrutzki, Martina

AU - Blank, Christian

PY - 2019/1/1

Y1 - 2019/1/1

UR - https://www.scopus.com/pages/publications/85058680214

U2 - 10.1016/j.ejca.2018.11.018

DO - 10.1016/j.ejca.2018.11.018

M3 - Article

SN - 0959-8049

VL - 107

SP - 175

EP - 185

JO - Eur. J. Cancer

JF - Eur. J. Cancer

M1 - PMID: 30580112

ER -

An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma: Final analysis and a validated prognostic scoring system

Research Beacons, Institutes and Platforms

UN SDGs

Access to Document

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