Abstract
Although a substantial part of the genetic risk for developing adult and juvenile IIM lies within the major histocompatibility complex, recent research suggests that genetic regions outside of the major histocompatibility complex are also potentially involved in conferring IIM disease susceptibility, although with more modest effect sizes. An ongoing and internationally coordinated IIM genome-wide association scan may provide further insights into IIM immunogenetics. © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins.
| Original language | English |
|---|---|
| Pages (from-to) | 588-593 |
| Number of pages | 5 |
| Journal | Current Opinion in Rheumatology |
| Volume | 21 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Nov 2009 |
Keywords
- Autoantibodies
- Human leukocyte antigen
- Myositis
- Single nucleotide polymorphisms
Fingerprint
Dive into the research topics of 'An update on the immunogenetics of idiopathic inflammatory myopathies: Major histocompatibility complex and beyond'. Together they form a unique fingerprint.Projects
- 1 Active
-
MMRG: Manchester Myositis Research Group
Chinoy, H. (PI), Lamb, J. (PI), Ollier, W. (PI), Rothwell, S. (CoI), Lilleker, J. (CoI), Oldroyd, A. (PGR student), Snedden, A. (PGR student), Platt, H. (Support team) & New, P. (Support team)
1/01/10 → …
Project: Research
File
Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver