Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient

Modhusudon Shaha; Palash Kumar Sarker; Md Saddam Hossain; Keshob Chandra Das; Munira Jahan; Shuvra Kanti Dey; Shahina Tabassum; Abu Hashem; Md Salimullah; Ashesh Kumar Chowdhury; Paul Klapper; Mohammad Ariful Islam

doi:10.5256/f1000research.16434.r35849

Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient

Modhusudon Shaha, Palash Kumar Sarker, Md Saddam Hossain, Keshob Chandra Das, Munira Jahan, Shuvra Kanti Dey, Shahina Tabassum, Abu Hashem, Md Salimullah^*, Ashesh Kumar Chowdhury, Paul Klapper, Mohammad Ariful Islam

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a HBV infected patient. Complete genome analysis revealed that the isolated strain was a non-recombinant wild type and had several regular substitutions in the reverse transcriptase domain and small surface proteins of HBV. This study may help clinicians and scientists gain in-depth knowledge on the current substitutions of HBV/C2 genome and to identify potential therapies against HBV infections.

Original language	English
Article number	1023
Journal	F1000Research
Volume	7
DOIs	https://doi.org/10.5256/f1000research.16434.r35849
Publication status	Published - 10 Sept 2018

Keywords

Bangladesh
Chronic
HBV/C2
Non-recombinant

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.5256/f1000research.16434.r35849

Cite this

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title = "Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient",

abstract = "The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a HBV infected patient. Complete genome analysis revealed that the isolated strain was a non-recombinant wild type and had several regular substitutions in the reverse transcriptase domain and small surface proteins of HBV. This study may help clinicians and scientists gain in-depth knowledge on the current substitutions of HBV/C2 genome and to identify potential therapies against HBV infections.",

keywords = "Bangladesh, Chronic, HBV/C2, Non-recombinant",

author = "Modhusudon Shaha and Sarker, \{Palash Kumar\} and Hossain, \{Md Saddam\} and Das, \{Keshob Chandra\} and Munira Jahan and Dey, \{Shuvra Kanti\} and Shahina Tabassum and Abu Hashem and Md Salimullah and Chowdhury, \{Ashesh Kumar\} and Paul Klapper and Islam, \{Mohammad Ariful\}",

year = "2018",

month = sep,

day = "10",

doi = "10.5256/f1000research.16434.r35849",

language = "English",

volume = "7",

journal = "F1000Research",

issn = "2046-1402",

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}

TY - JOUR

T1 - Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient

AU - Shaha, Modhusudon

AU - Sarker, Palash Kumar

AU - Hossain, Md Saddam

AU - Das, Keshob Chandra

AU - Jahan, Munira

AU - Dey, Shuvra Kanti

AU - Tabassum, Shahina

AU - Hashem, Abu

AU - Salimullah, Md

AU - Chowdhury, Ashesh Kumar

AU - Klapper, Paul

AU - Islam, Mohammad Ariful

PY - 2018/9/10

Y1 - 2018/9/10

N2 - The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a HBV infected patient. Complete genome analysis revealed that the isolated strain was a non-recombinant wild type and had several regular substitutions in the reverse transcriptase domain and small surface proteins of HBV. This study may help clinicians and scientists gain in-depth knowledge on the current substitutions of HBV/C2 genome and to identify potential therapies against HBV infections.

AB - The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a HBV infected patient. Complete genome analysis revealed that the isolated strain was a non-recombinant wild type and had several regular substitutions in the reverse transcriptase domain and small surface proteins of HBV. This study may help clinicians and scientists gain in-depth knowledge on the current substitutions of HBV/C2 genome and to identify potential therapies against HBV infections.

KW - Bangladesh

KW - Chronic

KW - HBV/C2

KW - Non-recombinant

UR - https://www.scopus.com/pages/publications/85053462715

U2 - 10.5256/f1000research.16434.r35849

DO - 10.5256/f1000research.16434.r35849

M3 - Review article

C2 - 30228877

AN - SCOPUS:85053462715

SN - 2046-1402

VL - 7

JO - F1000Research

JF - F1000Research

M1 - 1023

ER -

Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient

Abstract

Keywords

UN SDGs

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