Angiogenesis inhibitors in the treatment of lung cancer

Fiona Blackhall, Frances A Shepherd

Research output: Contribution to journalReview article

Abstract

Angiogenesis is believed to play a critical role in cancer; however, antiangiogenic therapy has not been demonstrated to improve the survival of patients who have lung cancer. In this article, the evidence that supports a role for angiogenesis in the pathogenesis of lung cancer, trials of antiangiogenic agents in lung cancer performed to date, and the lessons learned from these studies are discussed.
Original languageEnglish
Pages (from-to)1121-1141
JournalHematology/Oncology Clinics of North America
Volume18
Issue number5
Publication statusPublished - 1 Mar 2005

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