Angiotropic lymphoma with endocrine involvement

J. H. Shanks, M. Harris, A. J. Howat, A. J. Freemont

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Aims: Two cases of angiotropic high-grade B-cell lymphoma are described in which involvement of endocrine glands was a prominent feature. Methods and results: One patient had marked unilateral adrenomegaly due to lymphoma within adrenal blood vessels. He is alive 5 years after presentation following combination chemotherapy. The diagnosis was made at autopsy in the second patient who presented with pyrexia of unknown origin and had hypothyroidism and a thyroid nodule. The thyroid gland and pituitary showed striking involvement by angiotropic lymphoma and the thyroid nodule was a cavernous haemangioma heavily colonized by lymphoma cells. Conclusions: Our cases illustrate endocrine organ manifestations of this rare disease. The condition may respond to combination chemotherapy.
    Original languageEnglish
    Pages (from-to)161-166
    Number of pages5
    JournalHistopathology
    Volume31
    Issue number2
    Publication statusPublished - 1997

    Keywords

    • Adrenal gland
    • Angiotropic lymphoma
    • Cavernous haemangioma
    • Pituitary gland
    • Thyroid gland

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