Abstract
Wound healing in adult mammals proceeds by a series of overlapping highly coordinated events. Dermal wound repair commences with the arrest of hemorrhage followed by an inflammatory response, re-epithelialization of the wound, and formation of granulation tissue within the wound space, culminating in the production of a scar. In order to study the processes involved in the repair of wounded tissue, we have developed a rodent model utilizing full thickness incisional and excisional dermal wounds, which allow for macroscopic observations and also provide tissue for the histological and immunocytochemical analysis of acute wounds and scarring.
| Original language | English |
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| Title of host publication | Methods in molecular medicine|Methods Mol Med |
| Pages | 223-235 |
| Number of pages | 12 |
| Volume | 117 |
| Publication status | Published - 2005 |