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Antagonizing Self-Renewal in Acute Myeloid Leukemia: ID2 Takes the Stage

Research output: Contribution to journal › Article › peer-review

Abstract

E proteins and their functional antagonists, the ID proteins, have significant roles in normal hematopoiesis. In this issue of Cancer Cell, Ghisi et al. show that high ID2 levels antagonize self-renewal and promote differentiation of leukemic stem cells in the MLL-translocated molecular subtype of acute myeloid leukemia.

Original languageEnglish
Pages (from-to)5-7
Number of pages3
JournalCancer Cell
Volume30
Issue number1
DOIs
Publication statusPublished - 11 Jul 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Journal Article

Research Highlights, Institutes and Platforms

  • Manchester Cancer Research Centre

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