Anterior chamber inflammation grading methods: A critical review

Hnin Hnin Oo; Madhuvanthi Mohan; Wenjun Song; William Rojas-Carabali; Edmund Tsui; Alejandra de-la-Torre; Carlos Cifuentes-González; Andres Rousselot; Sangly P Srinivas; Tariq Aslam; Vishali Gupta; Rupesh Agrawal

doi:10.1016/j.survophthal.2023.10.005

Anterior chamber inflammation grading methods: A critical review

Hnin Hnin Oo, Madhuvanthi Mohan, Wenjun Song, William Rojas-Carabali, Edmund Tsui, Alejandra de-la-Torre, Carlos Cifuentes-González, Andres Rousselot, Sangly P Srinivas, Tariq Aslam, Vishali Gupta, Rupesh Agrawal

Optometry

Research output: Contribution to journal › Review article › peer-review

Abstract

Assessing anterior chamber (AC) inflammation is highly subjective and challenging. Although various grading systems attempt to offer objectivity and standardization, the clinical assessment has high interobserver variability. Traditional techniques, such as laser flare meter and fluorophotometry, are not widely used since they are time-consuming. With the development of optical coherence tomography with high sensitivity, direct imaging offers an excellent alternative to objectively assess inflammation with the potential for automated analysis. We describe various AC inflammation grading methods and discuss their utility, advantages, and disadvantages.

Original language	English
Pages (from-to)	253-264
Number of pages	12
Journal	Survey of ophthalmology
Volume	69
Issue number	2
Early online date	5 Oct 2023
DOIs	https://doi.org/10.1016/j.survophthal.2023.10.005
Publication status	Published - 1 Mar 2024

Keywords

Anterior chamber inflammation
Anterior uveitis
Cells
Flare
Measurement
Optical coherence tomography

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10.1016/j.survophthal.2023.10.005

Cite this

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abstract = "Assessing anterior chamber (AC) inflammation is highly subjective and challenging. Although various grading systems attempt to offer objectivity and standardization, the clinical assessment has high interobserver variability. Traditional techniques, such as laser flare meter and fluorophotometry, are not widely used since they are time-consuming. With the development of optical coherence tomography with high sensitivity, direct imaging offers an excellent alternative to objectively assess inflammation with the potential for automated analysis. We describe various AC inflammation grading methods and discuss their utility, advantages, and disadvantages.",

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AU - Oo, Hnin Hnin

AU - Mohan, Madhuvanthi

AU - Song, Wenjun

AU - Rojas-Carabali, William

AU - Tsui, Edmund

AU - de-la-Torre, Alejandra

AU - Cifuentes-González, Carlos

AU - Rousselot, Andres

AU - Srinivas, Sangly P

AU - Aslam, Tariq

AU - Gupta, Vishali

AU - Agrawal, Rupesh

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KW - Anterior chamber inflammation

KW - Anterior uveitis

KW - Cells

KW - Flare

KW - Measurement

KW - Optical coherence tomography

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JO - Survey of ophthalmology

JF - Survey of ophthalmology

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Anterior chamber inflammation grading methods: A critical review

Abstract

Keywords

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