Aortic augmentation index: Reference values in a large unselected population by means of the sphygmocor device

Julie H. Janner; Nina S. Godtfredsen; Steen Ladelund; Jørgen Vestbo; Eva Prescott

doi:10.1038/ajh.2009.234

Aortic augmentation index: Reference values in a large unselected population by means of the sphygmocor device

Julie H. Janner, Nina S. Godtfredsen, Steen Ladelund, Jørgen Vestbo, Eva Prescott

Research output: Contribution to journal › Article › peer-review

Abstract

BackgroundArterial stiffness and pulse wave reflection are associated with cardiovascular disease (CVD). Pulse wave analyses (PWAs) allow the estimation of the central augmentation index (AIx), a measurement of pulse wave reflection. To understand the predictive role of AIx, reference values for AIx are needed.MethodsThis population study is based on 4,561 subjects from The Copenhagen City Heart Study, an ongoing epidemiological survey started in 1976, including subjects randomly chosen from the population in Copenhagen, Denmark. We calculated and internally validated reference values of AIx measured by the SphygmoCor device in a cohort without known CVD or diabetes, and with low risk of CVD according to HeartScore using gender-specific multiple regression analyses adjusting for age, heart rate, and height.ResultsAIx was significantly higher in women than in men, 30% vs. 22%, (P

Original language	English
Pages (from-to)	180-185
Number of pages	5
Journal	American Journal of Hypertension
Volume	23
Issue number	2
DOIs	https://doi.org/10.1038/ajh.2009.234
Publication status	Published - Feb 2010

Keywords

AIx
Arterial stiffness
Augmentation index
Blood pressure
Cardiovascular disease
Epidemiology
Hypertension
Reference values

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/ajh.2009.234

Cite this

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AU - Godtfredsen, Nina S.

AU - Ladelund, Steen

AU - Vestbo, Jørgen

AU - Prescott, Eva

PY - 2010/2

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KW - Arterial stiffness

KW - Augmentation index

KW - Blood pressure

KW - Cardiovascular disease

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KW - Hypertension

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Aortic augmentation index: Reference values in a large unselected population by means of the sphygmocor device

Abstract

Keywords

UN SDGs

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