Application of carbon nanotubes in neurology: Clinical perspectives and toxicological risks

Antonio Nunes, Khuloud Al-Jamal, Takeshi Nakajima, Marwan Hariz, Kostas Kostarelos

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Nanomedicine is an emerging field that proposes the application of precisely engineered nanomaterials for the prevention, diagnosis and therapy of certain diseases, including neurological pathologies. Carbon nanotubes (CNT) are a new class of nanomaterials, which have been shown to be promising in different areas of nanomedicine. In this review, the application of CNT interfacing with the central nervous system (CNS) will be described, and representative examples of neuroprosthetic devices, such as neuronal implants and electrodes will be discussed. Furthermore, the possible application of CNT-based materials as regenerative matrices of neuronal tissue and as delivery systems for the therapy of CNS will be presented. © Springer-Verlag 2012.
    Original languageEnglish
    Pages (from-to)1009-1020
    Number of pages11
    JournalArchives of Toxicology
    Volume86
    Issue number7
    DOIs
    Publication statusPublished - Jul 2012

    Keywords

    • Carbon nanotubes
    • CNS neurotoxicity
    • Neurology
    • Neuroregeneration
    • Therapy

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