Application of physiologically based pharmacokinetic (PBPK) modelling for prediction of complex drug-drug interactions (DDIs) involving inhibition of OATP1B1-mediated uptake and CYP2C8 metabolism by gemfibrozil and its major metabolite gemfibrozil 1-O-β glucuronide

Amin Rostami-Hochaghan; H Humphries; ZE Barter; A Rostami-Hodjegan; Yeo K Rowland

Application of physiologically based pharmacokinetic (PBPK) modelling for prediction of complex drug-drug interactions (DDIs) involving inhibition of OATP1B1-mediated uptake and CYP2C8 metabolism by gemfibrozil and its major metabolite gemfibrozil 1-O-β glucuronide

Amin Rostami-Hochaghan
, H Humphries
, ZE Barter
, A Rostami-Hodjegan
, Yeo K Rowland

Research output: Contribution to conference › Poster

Original language	English
Publication status	Published - Mar 2013
Event	ASCPT 2013 Annual Meeting - Indianapolis, USA Duration: 5 Mar 2013 → 9 Mar 2013

Conference

Conference	ASCPT 2013 Annual Meeting
City	Indianapolis, USA
Period	5/03/13 → 9/03/13

Cite this

Rostami-Hochaghan, A., Humphries, H., Barter, ZE., Rostami-Hodjegan, A., & Rowland, Y. K. (2013). Application of physiologically based pharmacokinetic (PBPK) modelling for prediction of complex drug-drug interactions (DDIs) involving inhibition of OATP1B1-mediated uptake and CYP2C8 metabolism by gemfibrozil and its major metabolite gemfibrozil 1-O-β glucuronide. Poster session presented at ASCPT 2013 Annual Meeting, Indianapolis, USA.

Rostami-Hochaghan, Amin ; Humphries, H ; Barter, ZE et al. / Application of physiologically based pharmacokinetic (PBPK) modelling for prediction of complex drug-drug interactions (DDIs) involving inhibition of OATP1B1-mediated uptake and CYP2C8 metabolism by gemfibrozil and its major metabolite gemfibrozil 1-O-β glucuronide. Poster session presented at ASCPT 2013 Annual Meeting, Indianapolis, USA.

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title = "Application of physiologically based pharmacokinetic (PBPK) modelling for prediction of complex drug-drug interactions (DDIs) involving inhibition of OATP1B1-mediated uptake and CYP2C8 metabolism by gemfibrozil and its major metabolite gemfibrozil 1-O-β glucuronide",

author = "Amin Rostami-Hochaghan and H Humphries and ZE Barter and A Rostami-Hodjegan and Rowland, \{Yeo K\}",

year = "2013",

month = mar,

language = "English",

note = "ASCPT 2013 Annual Meeting ; Conference date: 05-03-2013 Through 09-03-2013",

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Rostami-Hochaghan, A, Humphries, H, Barter, ZE, Rostami-Hodjegan, A & Rowland, YK 2013, 'Application of physiologically based pharmacokinetic (PBPK) modelling for prediction of complex drug-drug interactions (DDIs) involving inhibition of OATP1B1-mediated uptake and CYP2C8 metabolism by gemfibrozil and its major metabolite gemfibrozil 1-O-β glucuronide', ASCPT 2013 Annual Meeting, Indianapolis, USA, 5/03/13 - 9/03/13.

Application of physiologically based pharmacokinetic (PBPK) modelling for prediction of complex drug-drug interactions (DDIs) involving inhibition of OATP1B1-mediated uptake and CYP2C8 metabolism by gemfibrozil and its major metabolite gemfibrozil 1-O-β glucuronide. / Rostami-Hochaghan, Amin; Humphries, H; Barter, ZE et al.
2013. Poster session presented at ASCPT 2013 Annual Meeting, Indianapolis, USA.

Research output: Contribution to conference › Poster

TY - CONF

T1 - Application of physiologically based pharmacokinetic (PBPK) modelling for prediction of complex drug-drug interactions (DDIs) involving inhibition of OATP1B1-mediated uptake and CYP2C8 metabolism by gemfibrozil and its major metabolite gemfibrozil 1-O-β glucuronide

AU - Rostami-Hochaghan, Amin

AU - Humphries, H

AU - Barter, ZE

AU - Rostami-Hodjegan, A

AU - Rowland, Yeo K

PY - 2013/3

Y1 - 2013/3

M3 - Poster

T2 - ASCPT 2013 Annual Meeting

Y2 - 5 March 2013 through 9 March 2013

ER -

Rostami-Hochaghan A, Humphries H, Barter ZE, Rostami-Hodjegan A, Rowland YK. Application of physiologically based pharmacokinetic (PBPK) modelling for prediction of complex drug-drug interactions (DDIs) involving inhibition of OATP1B1-mediated uptake and CYP2C8 metabolism by gemfibrozil and its major metabolite gemfibrozil 1-O-β glucuronide. 2013. Poster session presented at ASCPT 2013 Annual Meeting, Indianapolis, USA.