Application of surface enhanced Raman scattering to the solution based detection of a popular legal high, 5,6-methylenedioxy-2-aminoindane (MDAI)

Samuel Mabbott; Omar Alharbi; Kate Groves; Royston Goodacre

doi:10.1039/c5an00591d

Application of surface enhanced Raman scattering to the solution based detection of a popular legal high, 5,6-methylenedioxy-2-aminoindane (MDAI)

Samuel Mabbott, Omar Alharbi, Kate Groves, Royston Goodacre

Research output: Contribution to journal › Article › peer-review

Abstract

The ever increasing numbers and users of designer drugs means that analytical techniques have to evolve constantly to facilitate their identification and detection. We report that surface enhanced Raman scattering (SERS) offers a relatively fast and inexpensive method for the detection of MDAI at low concentrations. Careful optimisation of the silver sol, and salt concentrations was undertaken to ensure the SERS analysis was both reproducible and sensitive. The optimised system demonstrated acceptable peak variations of less than 15% RSD and resulted in a detection limit of just 8 ppm (5.4 × 10^-5 M).

Original language	English
Pages (from-to)	4399-4406
Number of pages	8
Journal	Analyst
Volume	140
Issue number	13
DOIs	https://doi.org/10.1039/c5an00591d
Publication status	Published - 7 Jul 2015

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Manchester Institute of Biotechnology

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AU - Goodacre, Royston

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Application of surface enhanced Raman scattering to the solution based detection of a popular legal high, 5,6-methylenedioxy-2-aminoindane (MDAI)

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