Applying Tensile and Compressive Force to Xenopus Animal Cap Tissue

Georgina K. Goddard, Nawseen Tarannum, Sarah Woolner

Research output: Contribution to journalArticlepeer-review

Abstract

Over many years, the Xenopus laevis embryo has provided a powerful model system to investigate how mechanical forces regulate cellular function. Here, we describe a system to apply reproducible tensile and compressive force to X. laevis animal cap tissue explants and to simultaneously assess cellular behavior using live confocal imaging.
Original languageEnglish
Pages (from-to)68-74
Number of pages7
JournalCold Spring Harbor Protocols
Volume2020
Issue number3
Early online date19 Dec 2019
DOIs
Publication statusPublished - Mar 2020

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