Approaches for monitoring nuclear translation.

Francisco J. Iborra, Dean A. Jackson, Peter R. Cook

    Research output: Contribution to journalArticlepeer-review


    The nuclear membrane is the defining feature of eukaryotes. It divides the cell into two functionally specialized compartments, and it is widely assumed that translation is restricted to only one: the cytoplasm. However, recent results suggest that some translation takes place in nuclei closely coupled to transcription. Various labeling techniques are described that enable nascent peptides to be labeled and then localized wherever they might be in the cell.
    Original languageEnglish
    Pages (from-to)103-114
    Number of pages11
    JournalMethods in Molecular Biology
    Publication statusPublished - 2004


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