Approaches for monitoring nuclear translation.

Francisco J. Iborra; Dean A. Jackson; Peter R. Cook

Approaches for monitoring nuclear translation.

Francisco J. Iborra, Dean A. Jackson, Peter R. Cook

Research output: Contribution to journal › Article › peer-review

Abstract

The nuclear membrane is the defining feature of eukaryotes. It divides the cell into two functionally specialized compartments, and it is widely assumed that translation is restricted to only one: the cytoplasm. However, recent results suggest that some translation takes place in nuclei closely coupled to transcription. Various labeling techniques are described that enable nascent peptides to be labeled and then localized wherever they might be in the cell.

Original language	English
Pages (from-to)	103-114
Number of pages	11
Journal	Methods in Molecular Biology
Volume	257
Publication status	Published - 2004

Cite this

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title = "Approaches for monitoring nuclear translation.",

abstract = "The nuclear membrane is the defining feature of eukaryotes. It divides the cell into two functionally specialized compartments, and it is widely assumed that translation is restricted to only one: the cytoplasm. However, recent results suggest that some translation takes place in nuclei closely coupled to transcription. Various labeling techniques are described that enable nascent peptides to be labeled and then localized wherever they might be in the cell.",

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AU - Cook, Peter R.

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AB - The nuclear membrane is the defining feature of eukaryotes. It divides the cell into two functionally specialized compartments, and it is widely assumed that translation is restricted to only one: the cytoplasm. However, recent results suggest that some translation takes place in nuclei closely coupled to transcription. Various labeling techniques are described that enable nascent peptides to be labeled and then localized wherever they might be in the cell.

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SN - 1064-3745

VL - 257

SP - 103

EP - 114

JO - Methods in Molecular Biology

JF - Methods in Molecular Biology

ER -

Approaches for monitoring nuclear translation.

Abstract

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