Approaches to attribution of detrimental health effects to occupational ionizing radiation exposure and their application in compensation programmes for cancer: a practical guide

Shengli Niu, Pascal Deboodt, Hajo Zeeb, Richard Wakeford

Research output: Book/ReportBook

Abstract

Ionizing radiation can cause adverse health effects in humans. These effects fall
into two categories: deterministic and stochastic health events. Deterministic effects of
ionizing radiation in humans are the result of whole-body or local exposures that cause
sufficient cell damage or cell killing to impair function in the irradiated tissue or organ.
Stochastic health effects involve the non-lethal modification of a cell rather than its death.
This modification is conventionally considered to be due to mutation of the DNA of a cell
nucleus that can lead to cancer in the exposed individual if it occurs in a somatic cell. If
the affected cell is a germ cell, hereditary genetic anomalies in the descendants of the
exposed individual are another, though extremely rare, possible outcome
Original languageEnglish
PublisherInternational Labour Organization
Number of pages116
Volume73
ISBN (Print)9789221224136
Publication statusPublished - 23 Jun 2010

Publication series

NameOccupational Safety and Health Series
PublisherInternational Labour Organization
No.73

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