Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli

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• Active

  EPSRC Future Manufacturing Research Hub (Outline) Nigel Scrutton Jan 18

  Scrutton, N. (PI), Barran, P. (CoI), Green, A. (CoI), Shapira, P. (CoI), Takano, E. (CoI), Theodoropoulos, C. (CoI) & Turner, N. (CoI)

  1/04/19 → 31/03/26

  Project: Research

  • Biocatalyst 100%
  • Active Site 95%
  • Synthase 77%
  • Oxidoreductase 72%
  • Electron Transport 70%
• Finished

  Japan Partnering Award: Application of MS-Imaging and Metabolomics in Synthetic Biology Based Strain Improvement of Industrially Important Microbes

  Takano, E. (PI), Breitling, R. (CoI) & Hollywood, K. (CoI)

  1/07/16 → 30/06/20

  Project: Research

  • Synthetic Biology 100%
  • Microorganism 100%
  • Metabolomics 75%
  • Escherichia coli 50%
  • Terpene 50%

• Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals

  Scrutton, N. (PI), Azapagic, A. (CoI), Balmer, A. (CoI), Barran, P. (CoI), Breitling, R. (CoI), Delneri, D. (CoI), Dixon, N. (CoI), Faulon, J.-L. (CoI), Flitsch, S. (CoI), Goble, C. (CoI), Goodacre, R. (CoI), Hay, S. (CoI), Kell, D. (CoI), Leys, D. (CoI), Lloyd, J. (CoI), Lockyer, N. (CoI), Martin, P. (CoI), Micklefield, J. (CoI), Munro, A. (CoI), Pedrosa Mendes, P. (CoI), Randles, S. (CoI), Salehi Yazdi, F. (CoI), Shapira, P. (CoI), Takano, E. (CoI), Turner, N. (CoI) & Winterburn, J. (CoI)

  14/11/14 → 13/05/20

  Project: Research

  • Metabolite 100%
  • Metabolic 99%
  • Oxidoreductase 92%
  • Escherichia coli 89%
  • Biocatalyst 86%