Abstract
Background
Many patients with psoriasis have undiagnosed psoriatic arthritis. Low specificity is found with many PsA screening tools. A new instrument, the CONTEST questionnaire, was developed utilising the most discriminative items from existing instruments.
Objective
The aim of this study was to compare the CONTEST and PEST screening tools.
Methods
People attending secondary care clinics with psoriasis, but not PsA, completed the questionnaires, were assessed for function and quality of life, and had a physical examination. Patients thought to have PsA were compared to those without. The performance of CONTEST and PEST were compared using area under the receiver operating curve (AUC), and sensitivity and specificity at the previously published cut-offs.
Results
451 dermatology patients were approached, 35% were reviewed, and 27 (17%, 95% CI 12.3 – 21.7) had unidentified psoriatic arthritis. The sensitivity and specificity (95% CI) of PEST were 0.60 (0.42 – 0.78)/0.76 (0.69 – 0.83) and for CONTEST 0.53 (0.34 – 0.72)/0.71 (0.63 – 0.79). The confidence limits for the AUC overlapped (AUC for PEST 0.72 (0.61 – 0.84), for CONTEST 0.66 (0.54 – 0.77).
Conclusions
PEST and CONTEST questionnaires performed equally well, with no superiority of the new CONTEST tool.
Many patients with psoriasis have undiagnosed psoriatic arthritis. Low specificity is found with many PsA screening tools. A new instrument, the CONTEST questionnaire, was developed utilising the most discriminative items from existing instruments.
Objective
The aim of this study was to compare the CONTEST and PEST screening tools.
Methods
People attending secondary care clinics with psoriasis, but not PsA, completed the questionnaires, were assessed for function and quality of life, and had a physical examination. Patients thought to have PsA were compared to those without. The performance of CONTEST and PEST were compared using area under the receiver operating curve (AUC), and sensitivity and specificity at the previously published cut-offs.
Results
451 dermatology patients were approached, 35% were reviewed, and 27 (17%, 95% CI 12.3 – 21.7) had unidentified psoriatic arthritis. The sensitivity and specificity (95% CI) of PEST were 0.60 (0.42 – 0.78)/0.76 (0.69 – 0.83) and for CONTEST 0.53 (0.34 – 0.72)/0.71 (0.63 – 0.79). The confidence limits for the AUC overlapped (AUC for PEST 0.72 (0.61 – 0.84), for CONTEST 0.66 (0.54 – 0.77).
Conclusions
PEST and CONTEST questionnaires performed equally well, with no superiority of the new CONTEST tool.
| Original language | English |
|---|---|
| Journal | Journal of the European Academy of Dermatology and Venereology |
| Early online date | 26 Mar 2018 |
| DOIs | |
| Publication status | Published - 2018 |
Keywords
- screening
- psoriasis
- psoriatic arthritis
- diagnosis