Associations between UVR exposure and basal cell carcinoma site and histology

Tracy J. Lovatt; John T. Lear; Jean Bastrilles; Christina Wong; Christopher E M Griffiths; Sudarshan Ramachandran; Andrew G. Smith; Asad Salim; Anthony A. Fryer; Peter W. Jones; Richard C. Strange

doi:10.1016/j.canlet.2004.08.008

Associations between UVR exposure and basal cell carcinoma site and histology

Tracy J. Lovatt, John T. Lear, Jean Bastrilles, Christina Wong, Christopher E M Griffiths, Sudarshan Ramachandran, Andrew G. Smith, Asad Salim, Anthony A. Fryer, Peter W. Jones, Richard C. Strange

Research output: Contribution to journal › Article › peer-review

Abstract

While sunlight is critical in basal cell carcinoma (BCC) pathogenesis the relationship between exposure and tumor site and histology is unclear. We determined if tumor site (trunk or head/neck) or histology (nodular or superficial) is determined by exposure pattern. In 66 cases with truncal and 362 patients with head/neck BCC at first presentation, average hours exposure/year, intermittency score, childhood sunburning and skin type were not significantly associated with tumor site or histology. However, often sunbathing was associated with a five-fold increased risk of truncal BCC. Average sunbathing score was significantly greater in 22 cases with truncal compared with 325 cases with head/neck nodular tumors and also in 44 cases with superficial truncal compared with superficial head/neck BCC. Thus, sunbathing determined tumor site but not histology. © 2004 Elsevier Ireland Ltd. All rights reserved.

Original language	English
Pages (from-to)	191-197
Number of pages	6
Journal	Cancer Letters
Volume	216
Issue number	2
DOIs	https://doi.org/10.1016/j.canlet.2004.08.008
Publication status	Published - 28 Dec 2004

Keywords

Basal cell carcinoma
Head/neck BCC
Nodular histology
Superficial histology
Truncal BCC
Ultraviolet radiation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.canlet.2004.08.008

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@article{c614f5aa2178481ab31e777bec66925e,

title = "Associations between UVR exposure and basal cell carcinoma site and histology",

abstract = "While sunlight is critical in basal cell carcinoma (BCC) pathogenesis the relationship between exposure and tumor site and histology is unclear. We determined if tumor site (trunk or head/neck) or histology (nodular or superficial) is determined by exposure pattern. In 66 cases with truncal and 362 patients with head/neck BCC at first presentation, average hours exposure/year, intermittency score, childhood sunburning and skin type were not significantly associated with tumor site or histology. However, often sunbathing was associated with a five-fold increased risk of truncal BCC. Average sunbathing score was significantly greater in 22 cases with truncal compared with 325 cases with head/neck nodular tumors and also in 44 cases with superficial truncal compared with superficial head/neck BCC. Thus, sunbathing determined tumor site but not histology. {\textcopyright} 2004 Elsevier Ireland Ltd. All rights reserved.",

keywords = "Basal cell carcinoma, Head/neck BCC, Nodular histology, Superficial histology, Truncal BCC, Ultraviolet radiation",

author = "Lovatt, {Tracy J.} and Lear, {John T.} and Jean Bastrilles and Christina Wong and Griffiths, {Christopher E M} and Sudarshan Ramachandran and Smith, {Andrew G.} and Asad Salim and Fryer, {Anthony A.} and Jones, {Peter W.} and Strange, {Richard C.}",

year = "2004",

month = dec,

day = "28",

doi = "10.1016/j.canlet.2004.08.008",

language = "English",

volume = "216",

pages = "191--197",

journal = "Cancer Letters",

issn = "1872-7980",

publisher = "Elsevier BV",

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TY - JOUR

T1 - Associations between UVR exposure and basal cell carcinoma site and histology

AU - Lovatt, Tracy J.

AU - Lear, John T.

AU - Bastrilles, Jean

AU - Wong, Christina

AU - Griffiths, Christopher E M

AU - Ramachandran, Sudarshan

AU - Smith, Andrew G.

AU - Salim, Asad

AU - Fryer, Anthony A.

AU - Jones, Peter W.

AU - Strange, Richard C.

PY - 2004/12/28

Y1 - 2004/12/28

N2 - While sunlight is critical in basal cell carcinoma (BCC) pathogenesis the relationship between exposure and tumor site and histology is unclear. We determined if tumor site (trunk or head/neck) or histology (nodular or superficial) is determined by exposure pattern. In 66 cases with truncal and 362 patients with head/neck BCC at first presentation, average hours exposure/year, intermittency score, childhood sunburning and skin type were not significantly associated with tumor site or histology. However, often sunbathing was associated with a five-fold increased risk of truncal BCC. Average sunbathing score was significantly greater in 22 cases with truncal compared with 325 cases with head/neck nodular tumors and also in 44 cases with superficial truncal compared with superficial head/neck BCC. Thus, sunbathing determined tumor site but not histology. © 2004 Elsevier Ireland Ltd. All rights reserved.

AB - While sunlight is critical in basal cell carcinoma (BCC) pathogenesis the relationship between exposure and tumor site and histology is unclear. We determined if tumor site (trunk or head/neck) or histology (nodular or superficial) is determined by exposure pattern. In 66 cases with truncal and 362 patients with head/neck BCC at first presentation, average hours exposure/year, intermittency score, childhood sunburning and skin type were not significantly associated with tumor site or histology. However, often sunbathing was associated with a five-fold increased risk of truncal BCC. Average sunbathing score was significantly greater in 22 cases with truncal compared with 325 cases with head/neck nodular tumors and also in 44 cases with superficial truncal compared with superficial head/neck BCC. Thus, sunbathing determined tumor site but not histology. © 2004 Elsevier Ireland Ltd. All rights reserved.

KW - Basal cell carcinoma

KW - Head/neck BCC

KW - Nodular histology

KW - Superficial histology

KW - Truncal BCC

KW - Ultraviolet radiation

U2 - 10.1016/j.canlet.2004.08.008

DO - 10.1016/j.canlet.2004.08.008

M3 - Article

SN - 1872-7980

VL - 216

SP - 191

EP - 197

JO - Cancer Letters

JF - Cancer Letters

IS - 2

ER -

Associations between UVR exposure and basal cell carcinoma site and histology

Abstract

Keywords

UN SDGs

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