Associations between Viral and Bacterial Potential Pathogens in the Nasopharynx of Children with and Without Respiratory Symptoms.

Chrysanthi L Skevaki, Paraskevi Tsialta, Aikaterini I Trochoutsou, Ioanna Logotheti, Heidi Makrinioti, Styliani Taka, Evangelia Lebessi, Irene Paraskakis, Nikolaos G Papadopoulos, Maria N Tsolia

    Research output: Contribution to journalArticlepeer-review

    Abstract

    BACKGROUND: Nasopharyngeal bacterial colonization is necessary for subsequent respiratory and/or invasive infection. Our study aimed atcomparing nasopharyngeal bacterial colonization rates between children with and without symptoms of an acute viral respiratory tract infection (ARTI), and examining associations between identified microorganisms. METHODS: Children 3 months-6 years old with and without an ARTI were recruitedand a questionnaire was filled. Nasopharyngeal samples were examined for Streptococcus pneumoniae(SP), Haemophilusinfluenzae(HI), Moraxella catarrhalis (MC), Staphylococcus aureus (SA) and Streptococcus pyogenes(SPyo) by culture.Viruses were detected with polymerase chain reaction (PCR). RESULTS: Median age of the 386recruited children was 23.4 months, and 127 had no respiratory symptoms. More asymptomatic subjects were found negative for all bacteria tested (p
    Original languageEnglish
    JournalThe Pediatric infectious disease journal
    DOIs
    Publication statusPublished - 10 Aug 2015

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