Asymmetric hydrogenation of nitroalkenes using Clostridium sporogenes

Abbas Sadeghi, Dimitris Hatziantoniou, John M Gardiner, Gillian Stephens

    Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

    Abstract

    The growth conditions for prodn. of C sporogenes were optimized to obtain maximal biocatalytic activity in harvested cells. The reaction conditions for C = C redn. using harvested cells were also optimized. The efficiency of electron donors for reducing cinnamate was in the order hydrogen>phenylalanine>glucose. The enantiopurity of the nitroalkene product depended on substrate concn., incubation time and pH in the reaction. [on SciFinder (R)]
    Original languageEnglish
    Title of host publicationMajmoa-i Maghalat-i Sevomin Hemayesh Maliy Biotechnology Jomhoriy-i Islame-i Iran, Mashhad, Islamic Republic of Iran, Sept. 9-11, 2003
    Volume4
    Publication statusPublished - 2003

    Keywords

    • Clostridium sporogenes
    • Fermentation
    • Hydrogenation (asym. hydrogenation of nitroalkenes using Clostridium sporogenes)
    • pH (biol. effects of
    • asym. hydrogenation of nitroalkenes using Clostridium sporogenes)
    • Alkenes Role: BCP (Biochemical process), BIOL (Biological study), PROC (Process) (nitro
    • Alkanes Role: BMF (Bioindustrial manufacture), BIOL (Biological study), PREP (Preparation) (nitro
    • Clostridium nitroalkene hydrogenation

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