Atropisomers and near-atropisomers: Achieving stereoselectivity by exploiting the conformational preferences of aromatic amides

Jonathan Clayden

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The conformational preferences of aromatic amides are remarkably easy to control with a high degree of selectivity. This article reviews the consequences of this unusual form of stereocontrol, which enables for example the asymmetric synthesis of atropisomers and the ability to achieve remote stereocontrol by conformational relay.
    Original languageEnglish
    Pages (from-to)127-135
    Number of pages8
    JournalChemical Communications
    Issue number2
    DOIs
    Publication statusPublished - 21 Jan 2004

    Keywords

    • Amides Role: PEP (Physical, engineering or chemical process), PRP (Properties), PYP (Physical process), PROC (Process) (aryl; stereoselectivity by exploiting the conformational preferences of arom. amides); Asymmetric synthesis and induction; Atropisomers; Conformational transition; Stereoselective synthesis (stereoselectivity by exploiting the conformational preferences of arom. amides)

    Fingerprint

    Dive into the research topics of 'Atropisomers and near-atropisomers: Achieving stereoselectivity by exploiting the conformational preferences of aromatic amides'. Together they form a unique fingerprint.

    Cite this