Autologous osteochondral mosaicplasty or TruFit plugs for cartilage repair

Paul Hindle, Jane L Hendry, John F Keating, Leela C Biant

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE: Autologous osteochondral mosaicplasty and TruFit Bone graft substitute plugs are methods used to repair symptomatic articular cartilage defects in the adult knee. There have been no comparative studies of the two techniques.

METHODS: This retrospective study assessed functional outcome of patients using the EQ-5D, Knee Injury and Osteoarthritis Outcome Score (KOOS) and Modified Cincinnati scores at follow-up of 1-5 years.

RESULTS: There were 66 patients in the study (35 TruFit and 31 Mosaicplasty): 44 males and 22 females with a mean age of 37.3 years (SD 12.6). The mean BMI was 26.8. Thirty-six articular cartilage lesions were due to trauma, twenty-six due to osteochondritis dissecans and three due to non-specific degenerative change or unknown. There was no difference between the two groups age (n.s.), sex (n.s.), BMI (n.s.), defect location (n.s.) or aetiology (n.s.). The median follow-up was 22 months for the TruFit cohort and 30 months for the mosaicplasty group. There was no significant difference in the requirement for re-operation (n.s). Patients undergoing autologous mosaicplasty had a higher rate of returning to sport (p = 0.006), lower EQ-5D pain scores (p = 0.048) and higher KOOS activities of daily living (p = 0.029) scores. Sub-group analysis showed no difference related to the number of cases the surgeon performed. Patients requiring re-operation had lower outcome scores regardless of their initial procedure.

CONCLUSION: This study demonstrated significantly better outcomes using two validated outcome scores (KOOS, EQ-5D), and an ability to return to sport in those undergoing autologous mosaicplasty compared to those receiving TruFit plugs.

LEVEL OF EVIDENCE: IV.

Original languageEnglish
Pages (from-to)1235-40
Number of pages6
JournalKnee Surgery, Sports Traumatology, Arthroscopy
Volume22
Issue number6
DOIs
Publication statusPublished - Jun 2014

Keywords

  • Adult
  • Arthroplasty
  • Bone Substitutes
  • Cartilage, Articular/surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Knee Joint/surgery
  • Male
  • Middle Aged
  • Recovery of Function
  • Retrospective Studies
  • Treatment Outcome

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