Automated production support for the bioprocess industry

Barry Lennox, Kathryn Kipling, Jarka Glassey, Gary Montague, Mark Willis, Hugo Hiden

    Research output: Contribution to journalArticlepeer-review

    Abstract

    This paper describes the application of Artificial Intelligence and Multivariate Statistical Techniques to two industrial fermentation systems. In the first example, an Expert System is shown to provide tighter control of an important process parameter. This is shown to lead to improved consistency of operation. In the second application, Principal Component Analysis is applied to a final stage fermentation production facility. The results presented indicate that the algorithm can provide concise indicators of process faults that can be presented to the operators to assist them in taking suitable corrective actions.
    Original languageEnglish
    Pages (from-to)269-275
    Number of pages6
    JournalBiotechnology progress
    Volume18
    Issue number2
    DOIs
    Publication statusPublished - 2002

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