Automation of routine clinical chromosome analysis. I. Karyotyping by machine.

    Research output: Contribution to journalArticlepeer-review


    An automated karyotyping system suitable for widespread use in clinical laboratories is described. The software is implemented on a general-purpose, commercially available image analyzer (Magiscan 2) using TV input from a conventional research microscope with minimal modification. The analysis is automatic, but operator interaction is used to resolve difficulties. Extensive experience with a routine clinical workload shows that the system is robust and easy to use and that its use results in a substantially increased laboratory throughput.
    Original languageEnglish
    Pages (from-to)383-390
    Number of pages7
    JournalAnalytical and quantitative cytology and histology
    Issue number5
    Publication statusPublished - Oct 1987


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