Best practice in primary care pathology: review 10

W S A Smellie, N Shaw, R Bowley, M F Stewart, A M Kelly, P J Twomey, P R Chadwick, J B Houghton, J P Ng, A J McCulloch

Research output: Contribution to journalReview articlepeer-review


This tenth best practice review examines four series of common primary care questions in laboratory medicine: (i) antenatal testing in pregnant women; (ii) estimated glomerular filtration rate calculation; (iii) safety testing for methotrexate; and (iv) blood glucose measurement in diabetes. The review is presented in question-answer format, referenced for each question series. The recommendations represent a precis of guidance found using a standardised literature search of national and international guidance notes, consensus statements, health policy documents and evidence-based medicine reviews, supplemented by Medline Embase searches to identify relevant primary research documents. They are not standards but form a guide to be set in the clinical context. Most are consensus rather than evidence-based. They will be updated periodically to take account of new information.

Original languageEnglish
Pages (from-to)1195-204
Number of pages10
JournalJournal Of Clinical Pathology
Issue number11
Publication statusPublished - Nov 2007


  • Blood Glucose/analysis
  • Diabetes Mellitus, Type 2/diagnosis
  • Drug Monitoring/methods
  • Female
  • Glomerular Filtration Rate
  • Humans
  • Immunosuppressive Agents/adverse effects
  • Methotrexate/adverse effects
  • Patient Selection
  • Pregnancy
  • Prenatal Care/methods
  • Primary Health Care/methods


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