Abstract
The peroxynitrite anion and the nitrogen dioxide (radical) are important toxic species which can arise in vivo from nitric oxide. Both in vivo and in vitro cell protection is demonstrated for beta-carotene in the presence of vitamin E and vitamin C. A synergistic protection is observed compared to the individual anti-oxidants and this is explained in terms of an electron transfer reaction in which the beta-carotene radical is repaired by vitamin C.
| Original language | English |
|---|---|
| Pages (from-to) | 387-389 |
| Number of pages | 3 |
| Journal | FEBS Letters |
| Volume | 436 |
| Issue number | 3 |
| Publication status | Published - 9 Oct 1998 |
Keywords
- beta-carotene
- lymphocyte
- peroxynitrite
- nitrogen dioxide
- vitamin E
- vitamin C
Research Beacons, Institutes and Platforms
- Dalton Nuclear Institute