Bioengineering of cytochrome P450 OleTJE: How does substrate positioning affect the product distributions?

Biochemistry, Genetics and Molecular Biology

• Cytochrome P450 100%
• Wild Type 100%
• Active Site 100%
• Hydroxylation 100%
• Molecular Mechanic 50%
• Computer Model 50%
• Isozyme 50%
• Decarboxylation 50%
• Hydrogen Peroxide 50%
• Quantum Mechanics 50%

Chemistry

• Product Distribution 100%
• Cytochrome P450 100%
• Hydroxylation 66%
• Heme 66%
• Dioxygen 33%
• Density Functional Theory 33%
• Transition State 33%
• Radical Cation 33%
• Coordination Sphere 33%
• Decarboxylation 33%
• Chemoselectivity 33%
• Hydrogen Peroxide 33%
• Biofuel 33%
• Molecular Mechanic 33%
• Quantum Mechanics 33%