Bioinspired organic chemistry

Robert J. Mart, Simon J. Webb

    Research output: Contribution to journalArticlepeer-review

    Abstract

    As well as describing some bioinspired structural and functional mimics of the major classes of biomolecule, this year's review reflects the expanding scope of bioinspired research by including short sections on bioinspired materials and the prevention of amyloid plaque formation. Highlights in this review include: switchable antisense PNA that targets Zebrafish genes to give phenotype changes in Zebrafish embryos, a new method for screening ion channels directly from SDS-PAGE gels, a "chemical tongue" that detects metabolites in food products, and designed synthetic polypeptides that engage in simple enzyme-like catalysis. © The Royal Society of Chemistry.
    Original languageEnglish
    Pages (from-to)370-393
    Number of pages23
    JournalAnnual Reports on the Progress of Chemistry - Section B
    Volume104
    DOIs
    Publication statusPublished - 2008

    Keywords

    • Peptides Role: BPN (Biosynthetic preparation), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (antisense
    • review of bioinspired org. chem.)
    • Synthesis (biomimetic
    • Organic chemistry (review of bioinspired org. chem.)
    • Peptide nucleic acids
    • Peptides
    • Proteins Role: BPN (Biosynthetic preparation), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (review of bioinspired org. chem.)
    • Enzymes Role: CAT (Catalyst use), USES (Uses) (review of bioinspired org. chem.)
    • review bioinspired org chem

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