Blister fluid cytokines in cutaneous inflammatory bullous disorders

Lesley E. Rhodes; Ibrahim A. Hashim; P. Jeremy McLaughlin; Peter S. Friedmann

doi:10.1080/000155599750010689

Blister fluid cytokines in cutaneous inflammatory bullous disorders

Lesley E. Rhodes, Ibrahim A. Hashim, P. Jeremy McLaughlin, Peter S. Friedmann

Research output: Contribution to journal › Article › peer-review

Abstract

Cytokines are important regulators of immune and inflammatory reactions in the skin, and may contribute to inflammatory blister induction. We examined the profiles of interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) in fluid of spontaneous blisters in the immune-based inflammatory disorders bullous pemphigoid (8 patients), allergic contact dermatitis (5 patients) and toxic epidermal necrolysis (5 patients). These were compared with levels in 9 patients with burns, i.e. inflammatory blisters of non- immune aetiology, and 4 patients with blisters of physical origin. Very high levels of IL-6 were found in bullous pemphigoid and toxic epidermal necrolysis (p

Original language	English
Pages (from-to)	288-290
Number of pages	2
Journal	Acta Dermato-Venereologica
Volume	79
Issue number	4
DOIs	https://doi.org/10.1080/000155599750010689
Publication status	Published - 1999

Keywords

Blister formation
Interleukin-6
Tumour necrosis factor-α

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10.1080/000155599750010689

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title = "Blister fluid cytokines in cutaneous inflammatory bullous disorders",

abstract = "Cytokines are important regulators of immune and inflammatory reactions in the skin, and may contribute to inflammatory blister induction. We examined the profiles of interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) in fluid of spontaneous blisters in the immune-based inflammatory disorders bullous pemphigoid (8 patients), allergic contact dermatitis (5 patients) and toxic epidermal necrolysis (5 patients). These were compared with levels in 9 patients with burns, i.e. inflammatory blisters of non- immune aetiology, and 4 patients with blisters of physical origin. Very high levels of IL-6 were found in bullous pemphigoid and toxic epidermal necrolysis (p",

keywords = "Blister formation, Interleukin-6, Tumour necrosis factor-α",

author = "Rhodes, {Lesley E.} and Hashim, {Ibrahim A.} and McLaughlin, {P. Jeremy} and Friedmann, {Peter S.}",

year = "1999",

doi = "10.1080/000155599750010689",

language = "English",

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pages = "288--290",

journal = "Acta Dermato-Venereologica",

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T1 - Blister fluid cytokines in cutaneous inflammatory bullous disorders

AU - Rhodes, Lesley E.

AU - Hashim, Ibrahim A.

AU - McLaughlin, P. Jeremy

AU - Friedmann, Peter S.

PY - 1999

Y1 - 1999

N2 - Cytokines are important regulators of immune and inflammatory reactions in the skin, and may contribute to inflammatory blister induction. We examined the profiles of interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) in fluid of spontaneous blisters in the immune-based inflammatory disorders bullous pemphigoid (8 patients), allergic contact dermatitis (5 patients) and toxic epidermal necrolysis (5 patients). These were compared with levels in 9 patients with burns, i.e. inflammatory blisters of non- immune aetiology, and 4 patients with blisters of physical origin. Very high levels of IL-6 were found in bullous pemphigoid and toxic epidermal necrolysis (p

AB - Cytokines are important regulators of immune and inflammatory reactions in the skin, and may contribute to inflammatory blister induction. We examined the profiles of interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) in fluid of spontaneous blisters in the immune-based inflammatory disorders bullous pemphigoid (8 patients), allergic contact dermatitis (5 patients) and toxic epidermal necrolysis (5 patients). These were compared with levels in 9 patients with burns, i.e. inflammatory blisters of non- immune aetiology, and 4 patients with blisters of physical origin. Very high levels of IL-6 were found in bullous pemphigoid and toxic epidermal necrolysis (p

KW - Blister formation

KW - Interleukin-6

KW - Tumour necrosis factor-α

U2 - 10.1080/000155599750010689

DO - 10.1080/000155599750010689

M3 - Article

SN - 1651-2057

VL - 79

SP - 288

EP - 290

JO - Acta Dermato-Venereologica

JF - Acta Dermato-Venereologica

IS - 4

ER -

Blister fluid cytokines in cutaneous inflammatory bullous disorders

Abstract

Keywords

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