Body composition and bone status of children born to mothers with type 1 diabetes mellitus

M. Zulf Mughal, J. Eelloo, S. A. Roberts, M. Maresh, K. A. Ward, R. Ashby, C. P. Sibley, J. E. Adams

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background: Altered growth, body composition and abnormalities of skeletal mineralisation have been reported in offspring of mothers with type 1 and type 2 diabetes mellitus. Aims: The authors hypothesised that children born to mothers with type 1 diabetes mellitus (CDM) would be taller, have higher body mass index (BMI), greater fat mass, thicker diaphyseal bone cortices and reduced trabecular bone mineral density (BMD), as compared to those born to non-diabetic mothers. Methods: Anthropometric, body composition and bone parameters were assessed using dual-energy x-ray absorptiometry (DXA) and peripheral quantitative CT in 67 white Caucasian CDM (35 boys; age 5-18 years) and in 246 (121 boys) age-matched controls. Results: CDM were taller (p
    Original languageEnglish
    Pages (from-to)281-285
    Number of pages4
    JournalArchives of Disease in Childhood
    Volume95
    Issue number4
    DOIs
    Publication statusPublished - Apr 2010

    Keywords

    • CHILDREN

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