Body mass index and mild cognitive impairment among rural older adults in China: the moderating roles of gender and age

Yemin Yuan; Chenchao Zhou; Nan Zhang

doi:10.1186/s12888-021-03059-8

Body mass index and mild cognitive impairment among rural older adults in China: the moderating roles of gender and age

Yemin Yuan (Lead), Chenchao Zhou (Corresponding), Nan Zhang

Manchester Institute for Collaborative Research on Ageing

Research output: Contribution to journal › Article › peer-review

Abstract

Background
Evidence concerning the association between body mass index (BMI) and cognitive function among older people is inconsistent. This study aimed to investigate gender and age as moderators in association between BMI and mild cognitive impairment (MCI) among rural older adults.

Methods
Data were derived from the 2019 Health Service for Rural Elderly Families Survey in Shandong, China. In total, 3242 people aged 60 years and above were included in the analysis. Multilevel mixed-effects logistic regression was used to examine the moderating roles of gender and age, then further to explore the relationship between BMI and MCI.

Results
There were 601 (18.5%) participants with MCI. Compared with normal BMI group, low BMI group had a higher risk of MCI among older people [adjusted odds ratio (aOR) = 2.08, 95% confidence interval (CI): 1.26–3.44], women (aOR = 2.06, 95% CI: 1.35–3.12), or the older elderly aged ≥75 years old (aOR = 3.20, 95% CI: 1.34–7.45). This effect remained statistically significant among older women (aOR = 3.38, 95% CI: 1.69–6.73). Among older men, elevated BMI group had a higher risk of MCI (aOR = 2.32, 95% CI: 1.17–4.61) than normal BMI group.

Conclusions
Gender and age moderated the association between BMI and MCI among Chinese rural older adults. Older women with low BMI were more likely to have MCI, but older men with elevated BMI were more likely to have MCI. These findings suggest rural community managers strengthen the health management by grouping the weight of older people to prevent the risk of dementia.

Original language	English
Article number	54
Pages (from-to)	54
Journal	BMC Psychiatry
Volume	21
Issue number	1
DOIs	https://doi.org/10.1186/s12888-021-03059-8
Publication status	Published - 23 Jan 2021

Keywords

Aged
Aged, 80 and over
Body Mass Index
China/epidemiology
Cognition
Cognitive Dysfunction/epidemiology
Female
Humans
Male
Middle Aged
Risk Factors
Rural Population

Research Beacons, Institutes and Platforms

Manchester Institute for Collaborative Research on Ageing

Access to Document

10.1186/s12888-021-03059-8

https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-021-03059-8

Cite this

@article{05f736b10bbe46369ca5fa624b51edc4,

title = "Body mass index and mild cognitive impairment among rural older adults in China: the moderating roles of gender and age",

abstract = "BackgroundEvidence concerning the association between body mass index (BMI) and cognitive function among older people is inconsistent. This study aimed to investigate gender and age as moderators in association between BMI and mild cognitive impairment (MCI) among rural older adults.MethodsData were derived from the 2019 Health Service for Rural Elderly Families Survey in Shandong, China. In total, 3242 people aged 60 years and above were included in the analysis. Multilevel mixed-effects logistic regression was used to examine the moderating roles of gender and age, then further to explore the relationship between BMI and MCI.ResultsThere were 601 (18.5%) participants with MCI. Compared with normal BMI group, low BMI group had a higher risk of MCI among older people [adjusted odds ratio (aOR) = 2.08, 95% confidence interval (CI): 1.26–3.44], women (aOR = 2.06, 95% CI: 1.35–3.12), or the older elderly aged ≥75 years old (aOR = 3.20, 95% CI: 1.34–7.45). This effect remained statistically significant among older women (aOR = 3.38, 95% CI: 1.69–6.73). Among older men, elevated BMI group had a higher risk of MCI (aOR = 2.32, 95% CI: 1.17–4.61) than normal BMI group.ConclusionsGender and age moderated the association between BMI and MCI among Chinese rural older adults. Older women with low BMI were more likely to have MCI, but older men with elevated BMI were more likely to have MCI. These findings suggest rural community managers strengthen the health management by grouping the weight of older people to prevent the risk of dementia.",

keywords = "Aged, Aged, 80 and over, Body Mass Index, China/epidemiology, Cognition, Cognitive Dysfunction/epidemiology, Female, Humans, Male, Middle Aged, Risk Factors, Rural Population",

author = "Yemin Yuan and Chenchao Zhou and Nan Zhang",

note = "Funding Information: This work was supported by the National Natural Science Foundation of China [grant numbers 71774104, 71473152, 71974117]; the China Medical Board [grant number 16–-257]; Cheeloo Youth Scholar Grant; and Shandong University [grant numbers IFYT1810, 2012DX006]. The funding organizations had no role in the design of the study and collection, analysis and interpretation of data and in writing the manuscript. Funding Information: We are grateful to all participants for their effort. We thank the officials of local health agencies and staffs at the study sites for their cooperation. CZ designed the study, supervised the data collection, and revised the manuscript. YY performed all statistical analyses and drafted the manuscript. JL and NZ gave many valuable comments on the draft and also polished it. PF and ZJ helped to plan the study, including the investigation. CY, DZ and WH participated in data collection and statistical analysis. All authors read and approved the final manuscript. This work was supported by the National Natural Science Foundation of China [grant numbers 71774104, 71473152, 71974117]; the China Medical Board [grant number 16?-257]; Cheeloo Youth Scholar Grant; and Shandong University [grant numbers IFYT1810, 2012DX006]. The funding organizations had no role in the design of the study and collection, analysis and interpretation of data and in writing the manuscript. Our data may not be shared directly, because it is our teamwork; informed consent should be attained from all the team members. The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request. The protocol for this study was approved by the Ethical Committee of School of Public Health, Shandong University (approval number, 20181228). The investigation was conducted after the acquisition of written informed consent of all participants. The data used in this study was anonymised before its use. The authors declare that they have no competing interests. Publisher Copyright: {\textcopyright} 2021, The Author(s).",

year = "2021",

month = jan,

day = "23",

doi = "10.1186/s12888-021-03059-8",

language = "English",

volume = "21",

pages = "54",

journal = "BMC Psychiatry",

issn = "1471-244X",

publisher = "Springer Nature",

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TY - JOUR

T1 - Body mass index and mild cognitive impairment among rural older adults in China: the moderating roles of gender and age

AU - Zhang, Nan

A2 - Yuan, Yemin

A2 - Zhou, Chenchao

N1 - Funding Information: This work was supported by the National Natural Science Foundation of China [grant numbers 71774104, 71473152, 71974117]; the China Medical Board [grant number 16–-257]; Cheeloo Youth Scholar Grant; and Shandong University [grant numbers IFYT1810, 2012DX006]. The funding organizations had no role in the design of the study and collection, analysis and interpretation of data and in writing the manuscript. Funding Information: We are grateful to all participants for their effort. We thank the officials of local health agencies and staffs at the study sites for their cooperation. CZ designed the study, supervised the data collection, and revised the manuscript. YY performed all statistical analyses and drafted the manuscript. JL and NZ gave many valuable comments on the draft and also polished it. PF and ZJ helped to plan the study, including the investigation. CY, DZ and WH participated in data collection and statistical analysis. All authors read and approved the final manuscript. This work was supported by the National Natural Science Foundation of China [grant numbers 71774104, 71473152, 71974117]; the China Medical Board [grant number 16?-257]; Cheeloo Youth Scholar Grant; and Shandong University [grant numbers IFYT1810, 2012DX006]. The funding organizations had no role in the design of the study and collection, analysis and interpretation of data and in writing the manuscript. Our data may not be shared directly, because it is our teamwork; informed consent should be attained from all the team members. The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request. The protocol for this study was approved by the Ethical Committee of School of Public Health, Shandong University (approval number, 20181228). The investigation was conducted after the acquisition of written informed consent of all participants. The data used in this study was anonymised before its use. The authors declare that they have no competing interests. Publisher Copyright: © 2021, The Author(s).

PY - 2021/1/23

Y1 - 2021/1/23

N2 - BackgroundEvidence concerning the association between body mass index (BMI) and cognitive function among older people is inconsistent. This study aimed to investigate gender and age as moderators in association between BMI and mild cognitive impairment (MCI) among rural older adults.MethodsData were derived from the 2019 Health Service for Rural Elderly Families Survey in Shandong, China. In total, 3242 people aged 60 years and above were included in the analysis. Multilevel mixed-effects logistic regression was used to examine the moderating roles of gender and age, then further to explore the relationship between BMI and MCI.ResultsThere were 601 (18.5%) participants with MCI. Compared with normal BMI group, low BMI group had a higher risk of MCI among older people [adjusted odds ratio (aOR) = 2.08, 95% confidence interval (CI): 1.26–3.44], women (aOR = 2.06, 95% CI: 1.35–3.12), or the older elderly aged ≥75 years old (aOR = 3.20, 95% CI: 1.34–7.45). This effect remained statistically significant among older women (aOR = 3.38, 95% CI: 1.69–6.73). Among older men, elevated BMI group had a higher risk of MCI (aOR = 2.32, 95% CI: 1.17–4.61) than normal BMI group.ConclusionsGender and age moderated the association between BMI and MCI among Chinese rural older adults. Older women with low BMI were more likely to have MCI, but older men with elevated BMI were more likely to have MCI. These findings suggest rural community managers strengthen the health management by grouping the weight of older people to prevent the risk of dementia.

AB - BackgroundEvidence concerning the association between body mass index (BMI) and cognitive function among older people is inconsistent. This study aimed to investigate gender and age as moderators in association between BMI and mild cognitive impairment (MCI) among rural older adults.MethodsData were derived from the 2019 Health Service for Rural Elderly Families Survey in Shandong, China. In total, 3242 people aged 60 years and above were included in the analysis. Multilevel mixed-effects logistic regression was used to examine the moderating roles of gender and age, then further to explore the relationship between BMI and MCI.ResultsThere were 601 (18.5%) participants with MCI. Compared with normal BMI group, low BMI group had a higher risk of MCI among older people [adjusted odds ratio (aOR) = 2.08, 95% confidence interval (CI): 1.26–3.44], women (aOR = 2.06, 95% CI: 1.35–3.12), or the older elderly aged ≥75 years old (aOR = 3.20, 95% CI: 1.34–7.45). This effect remained statistically significant among older women (aOR = 3.38, 95% CI: 1.69–6.73). Among older men, elevated BMI group had a higher risk of MCI (aOR = 2.32, 95% CI: 1.17–4.61) than normal BMI group.ConclusionsGender and age moderated the association between BMI and MCI among Chinese rural older adults. Older women with low BMI were more likely to have MCI, but older men with elevated BMI were more likely to have MCI. These findings suggest rural community managers strengthen the health management by grouping the weight of older people to prevent the risk of dementia.

KW - Aged

KW - Aged, 80 and over

KW - Body Mass Index

KW - China/epidemiology

KW - Cognition

KW - Cognitive Dysfunction/epidemiology

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Risk Factors

KW - Rural Population

U2 - 10.1186/s12888-021-03059-8

DO - 10.1186/s12888-021-03059-8

M3 - Article

C2 - 33485307

SN - 1471-244X

VL - 21

SP - 54

JO - BMC Psychiatry

JF - BMC Psychiatry

IS - 1

M1 - 54

ER -

Body mass index and mild cognitive impairment among rural older adults in China: the moderating roles of gender and age

Abstract

Keywords

Research Beacons, Institutes and Platforms

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