C-reactive Protein as a Predictor of Prognosis in COPD.

M Dahl; J Vestbo; P Lange; SE Bojesen; A Tybjaerg-Hansen; BG. Nordestgaard

C-reactive Protein as a Predictor of Prognosis in COPD.

M Dahl, J Vestbo, P Lange, SE Bojesen, A Tybjaerg-Hansen, BG. Nordestgaard

Research output: Contribution to journal › Article › peer-review

Abstract

RATIONALE: Patients with COPD have an ongoing systemic inflammation, which can be assessed by measuring serum C-reactive protein (CRP). OBJECTIVE: To determine whether increased serum CRP in individuals with airway obstruction predict future hospitalization and death from COPD. METHODS: We performed a cohort study with a median of 8-years follow-up of 1,302 individuals with airway obstruction selected from the ongoing Copenhagen City Heart Study. MEASUREMENTS AND MAIN RESULTS: We measured serum CRP at baseline, and recorded COPD admissions and deaths as outcomes. During follow-up, 185 (14%) individuals were hospitalized due to COPD and 83 (6%) died from COPD. Incidences of COPD hospitalization and COPD death were increased in individuals with baseline CRP >3mg/L vs. 3mg/L vs.

Original language	English
Journal	American Journal of Respiratory and Critical Care Medicine
Publication status	Published - 1 Feb 2006

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title = "C-reactive Protein as a Predictor of Prognosis in COPD.",

abstract = "RATIONALE: Patients with COPD have an ongoing systemic inflammation, which can be assessed by measuring serum C-reactive protein (CRP). OBJECTIVE: To determine whether increased serum CRP in individuals with airway obstruction predict future hospitalization and death from COPD. METHODS: We performed a cohort study with a median of 8-years follow-up of 1,302 individuals with airway obstruction selected from the ongoing Copenhagen City Heart Study. MEASUREMENTS AND MAIN RESULTS: We measured serum CRP at baseline, and recorded COPD admissions and deaths as outcomes. During follow-up, 185 (14%) individuals were hospitalized due to COPD and 83 (6%) died from COPD. Incidences of COPD hospitalization and COPD death were increased in individuals with baseline CRP >3mg/L vs. 3mg/L vs.",

author = "M Dahl and J Vestbo and P Lange and SE Bojesen and A Tybjaerg-Hansen and BG. Nordestgaard",

year = "2006",

month = feb,

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language = "English",

journal = " American Journal of Respiratory and Critical Care Medicine ",

issn = "1535-4970",

publisher = "American Thoracic Society",

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T1 - C-reactive Protein as a Predictor of Prognosis in COPD.

AU - Dahl, M

AU - Vestbo, J

AU - Lange, P

AU - Bojesen, SE

AU - Tybjaerg-Hansen, A

AU - Nordestgaard, BG.

PY - 2006/2/1

Y1 - 2006/2/1

N2 - RATIONALE: Patients with COPD have an ongoing systemic inflammation, which can be assessed by measuring serum C-reactive protein (CRP). OBJECTIVE: To determine whether increased serum CRP in individuals with airway obstruction predict future hospitalization and death from COPD. METHODS: We performed a cohort study with a median of 8-years follow-up of 1,302 individuals with airway obstruction selected from the ongoing Copenhagen City Heart Study. MEASUREMENTS AND MAIN RESULTS: We measured serum CRP at baseline, and recorded COPD admissions and deaths as outcomes. During follow-up, 185 (14%) individuals were hospitalized due to COPD and 83 (6%) died from COPD. Incidences of COPD hospitalization and COPD death were increased in individuals with baseline CRP >3mg/L vs. 3mg/L vs.

AB - RATIONALE: Patients with COPD have an ongoing systemic inflammation, which can be assessed by measuring serum C-reactive protein (CRP). OBJECTIVE: To determine whether increased serum CRP in individuals with airway obstruction predict future hospitalization and death from COPD. METHODS: We performed a cohort study with a median of 8-years follow-up of 1,302 individuals with airway obstruction selected from the ongoing Copenhagen City Heart Study. MEASUREMENTS AND MAIN RESULTS: We measured serum CRP at baseline, and recorded COPD admissions and deaths as outcomes. During follow-up, 185 (14%) individuals were hospitalized due to COPD and 83 (6%) died from COPD. Incidences of COPD hospitalization and COPD death were increased in individuals with baseline CRP >3mg/L vs. 3mg/L vs.

M3 - Article

SN - 1535-4970

JO - American Journal of Respiratory and Critical Care Medicine

JF - American Journal of Respiratory and Critical Care Medicine

ER -

C-reactive Protein as a Predictor of Prognosis in COPD.

Abstract

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