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Caelyx (stealth liposomal doxorubicin) in the treatment of advanced breast cancer

  • M. R. Ranson
  • , S. Cheeseman
  • , S. White
  • , J. Margison

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Anthracyclines are amongst the most active drugs in the treatment of breast cancer. Stealth liposomal doxorubicin (Caelyx, Doxil, Alza Pharmaceuticals Inc.) is a promising new agent under investigation for the treatment of breast cancer and other solid tumours. The liposomal encapsulation alters drug pharmacokinetics and leads to a marked change in toxicity profile compared to non-liposomal doxorubicin. The results of recently completed and ongoing clinical trials in breast cancer are reviewed. Copyright © 2001 Elsevier Science Ireland Ltd.
    Original languageEnglish
    Pages (from-to)115-120
    Number of pages5
    JournalCritical Reviews in Oncology/Hematology
    Volume37
    Issue number2
    DOIs
    Publication statusPublished - 2001

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • Breast cancer
    • Caelyx
    • Doxil
    • Doxorubicin
    • Liposome

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