Calcium-activated potassium channels and the regulation of vascular tone

Jonathan Ledoux, Matthias E. Werner, Joseph E. Brayden, Mark T. Nelson

    Research output: Contribution to journalArticlepeer-review


    Different calcium signals in the endothelium and smooth muscle target different types of Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium signals and targets represent multilayered opportunities for prevention and/or treatment of vascular dysfunctions. ©2006 Int. Union Physiol. Sci./Am. Physiol. Soc.
    Original languageEnglish
    Pages (from-to)69-79
    Number of pages10
    Issue number1
    Publication statusPublished - Feb 2006


    • Animals
    • Blood Pressure
    • physiology: Calcium
    • physiopathology: Cardiovascular Diseases
    • physiology: Endothelium, Vascular
    • Humans
    • physiology: Muscle, Smooth, Vascular
    • classification: Potassium Channels, Calcium-Activated
    • Signal Transduction


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