Calcium-activated potassium channels and the regulation of vascular tone

Jonathan Ledoux; Matthias E. Werner; Joseph E. Brayden; Mark T. Nelson

doi:10.1152/physiol.00040.2005

Calcium-activated potassium channels and the regulation of vascular tone

Jonathan Ledoux, Matthias E. Werner, Joseph E. Brayden, Mark T. Nelson

Research output: Contribution to journal › Article › peer-review

Abstract

Different calcium signals in the endothelium and smooth muscle target different types of Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium signals and targets represent multilayered opportunities for prevention and/or treatment of vascular dysfunctions. ©2006 Int. Union Physiol. Sci./Am. Physiol. Soc.

Original language	English
Pages (from-to)	69-79
Number of pages	10
Journal	Physiology
Volume	21
Issue number	1
DOIs	https://doi.org/10.1152/physiol.00040.2005
Publication status	Published - Feb 2006

Keywords

Animals
Blood Pressure
physiology: Calcium
physiopathology: Cardiovascular Diseases
physiology: Endothelium, Vascular
Humans
physiology: Muscle, Smooth, Vascular
classification: Potassium Channels, Calcium-Activated
Signal Transduction

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10.1152/physiol.00040.2005

http://physiologyonline.physiology.org/cgi/reprint/21/1/69

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title = "Calcium-activated potassium channels and the regulation of vascular tone",

abstract = "Different calcium signals in the endothelium and smooth muscle target different types of Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium signals and targets represent multilayered opportunities for prevention and/or treatment of vascular dysfunctions. {\textcopyright}2006 Int. Union Physiol. Sci./Am. Physiol. Soc.",

keywords = "Animals, Blood Pressure, physiology: Calcium, physiopathology: Cardiovascular Diseases, physiology: Endothelium, Vascular, Humans, physiology: Muscle, Smooth, Vascular, classification: Potassium Channels, Calcium-Activated, Signal Transduction",

author = "Jonathan Ledoux and Werner, {Matthias E.} and Brayden, {Joseph E.} and Nelson, {Mark T.}",

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AU - Werner, Matthias E.

AU - Brayden, Joseph E.

AU - Nelson, Mark T.

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AB - Different calcium signals in the endothelium and smooth muscle target different types of Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium signals and targets represent multilayered opportunities for prevention and/or treatment of vascular dysfunctions. ©2006 Int. Union Physiol. Sci./Am. Physiol. Soc.

KW - Animals

KW - Blood Pressure

KW - physiology: Calcium

KW - physiopathology: Cardiovascular Diseases

KW - physiology: Endothelium, Vascular

KW - Humans

KW - physiology: Muscle, Smooth, Vascular

KW - classification: Potassium Channels, Calcium-Activated

KW - Signal Transduction

U2 - 10.1152/physiol.00040.2005

DO - 10.1152/physiol.00040.2005

M3 - Article

SN - 1548-9213

VL - 21

SP - 69

EP - 79

JO - Physiology

JF - Physiology

IS - 1

ER -

Calcium-activated potassium channels and the regulation of vascular tone

Abstract

Keywords

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