Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory

Elisa A. M. Calvier, Thu Thuy Nguyen, Trevor N. Johnson, Amin Rostami-hodjegan, Dick Tibboel, Elke H. J. Krekels, Catherijne A. J. Knibbe

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Pharmacology, Toxicology and Pharmaceutical Science