Can the index of myocardial performance be used to detect acute cellular rejection after heart transplantation?

Malcolm I. Burgess, Rowland J. Bright-Thomas, Nizar Yonan, Simon G. Ray

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The index of myocardial performance (IMP), combining systolic and diastolic function, was measured in 50 orthotopic heart transplant recipients to determine if it could be used to detect acute rejection. It was calculated as the sum of the isovolumic contraction time (IVCT) and isovolumic relaxation time (IVRT) divided by the ejection time. Comparison of intrarecipient changes in Doppler intervals between rejection and nonrejection states demonstrated an increase in IVCT and decrease in IVRT during rejection with no significant change in the IMP. Rejection is likely to be best detected by assessing these parameters independently rather than by measuring the IMP. © 2003 by Excerpta Medica, Inc.
    Original languageEnglish
    Pages (from-to)308-311
    Number of pages3
    JournalAmerican Journal of Cardiology
    Volume92
    Issue number3
    DOIs
    Publication statusPublished - 1 Aug 2003

    Keywords

    • Echocardiography, Doppler
    • Female
    • physiopathology: Graft Rejection
    • immunology: Heart Transplantation
    • Human
    • Male
    • Middle Age
    • physiology: Myocardial Contraction
    • Predictive Value of Tests
    • Prospective Studies

    Fingerprint

    Dive into the research topics of 'Can the index of myocardial performance be used to detect acute cellular rejection after heart transplantation?'. Together they form a unique fingerprint.

    Cite this