Cardiac Toxicity of Thoracic Radiotherapy: Existing Evidence and Future Directions

Kathryn Banfill, Meredith Giuliani, Marianne Aznar, Kevin Franks, Alan Mcwilliam, Matthias Schmitt, Fei Sun, Marie Catherine Vozenin, Corinne Faivre Finn

Research output: Contribution to journalArticlepeer-review


The impact of radiotherapy on the heart has become an area of interest in recent years. Many different cardiac dose volume constraints have been associated with cardiac toxicity and survival however, no consistent constraint has been found. Many patients undergoing treatment for lung cancer have risk factors for cardiovascular disease or known cardiac comorbidities however, there is little evidence on the effects of radiotherapy on the heart in these patients. We aim to provide a summary of the existing literature on cardiac toxicity of lung cancer radiotherapy, propose strategies to avoid and manage cardiac toxicity and suggest avenues for future research.
Original languageEnglish
JournalJournal of Thoracic Oncology
Early online date3 Dec 2020
Publication statusE-pub ahead of print - 3 Dec 2020


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