Catalytic, PMe3-mediated conversion of secondary nitroalkanes to ketones: a very mild Nef-type process

Jordi Burés; Jaume Vilarrasa

doi:10.1016/j.tetlet.2007.11.110

Catalytic, PMe3-mediated conversion of secondary nitroalkanes to ketones: a very mild Nef-type process

Jordi Burés
, Jaume Vilarrasa

Research output: Contribution to journal › Article › peer-review

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Abstract

Aliph. secondary nitro compds. are converted to ketones at room temp., usually in 90-100% yields, by a one-pot reaction with 220-250 mol% of trimethylphosphine (PMe3) and 50-100 mol% of tBuC6H4SSC6H4 tBu or PhthN-SePh, or 20 mol% of both additives. Thus, very mild catalytic variants of the reductive Nef-like reactions are disclosed. [on SciFinder(R)]

Original language	English
Pages (from-to)	441-444
Number of pages	4
Journal	Tetrahedron Letters
Volume	49
DOIs	https://doi.org/10.1016/j.tetlet.2007.11.110
Publication status	Published - 2008

Keywords

aliph secondary nitroalkane trimethylphosphine Nef reaction ketone prepn Nef reaction reagent trimethylphosphine

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10.1016/j.tetlet.2007.11.110

Bures-2008-Catalytic, PMe3-medi

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title = "Catalytic, PMe3-mediated conversion of secondary nitroalkanes to ketones: a very mild Nef-type process",

abstract = "Aliph. secondary nitro compds. are converted to ketones at room temp., usually in 90-100\% yields, by a one-pot reaction with 220-250 mol\% of trimethylphosphine (PMe3) and 50-100 mol\% of tBuC6H4SSC6H4 tBu or PhthN-SePh, or 20 mol\% of both additives. Thus, very mild catalytic variants of the reductive Nef-like reactions are disclosed. [on SciFinder(R)]",

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author = "Jordi Bur{\'e}s and Jaume Vilarrasa",

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T1 - Catalytic, PMe3-mediated conversion of secondary nitroalkanes to ketones: a very mild Nef-type process

AU - Burés, Jordi

AU - Vilarrasa, Jaume

N1 - M1 - 3 CAPLUS AN 2007:1463537(Journal)

PY - 2008

Y1 - 2008

N2 - Aliph. secondary nitro compds. are converted to ketones at room temp., usually in 90-100% yields, by a one-pot reaction with 220-250 mol% of trimethylphosphine (PMe3) and 50-100 mol% of tBuC6H4SSC6H4 tBu or PhthN-SePh, or 20 mol% of both additives. Thus, very mild catalytic variants of the reductive Nef-like reactions are disclosed. [on SciFinder(R)]

AB - Aliph. secondary nitro compds. are converted to ketones at room temp., usually in 90-100% yields, by a one-pot reaction with 220-250 mol% of trimethylphosphine (PMe3) and 50-100 mol% of tBuC6H4SSC6H4 tBu or PhthN-SePh, or 20 mol% of both additives. Thus, very mild catalytic variants of the reductive Nef-like reactions are disclosed. [on SciFinder(R)]

KW - aliph secondary nitroalkane trimethylphosphine Nef reaction ketone prepn Nef reaction reagent trimethylphosphine

U2 - 10.1016/j.tetlet.2007.11.110

DO - 10.1016/j.tetlet.2007.11.110

M3 - Article

SN - 0040-4039

VL - 49

SP - 441

EP - 444

JO - Tetrahedron Letters

JF - Tetrahedron Letters

ER -

Catalytic, PMe3-mediated conversion of secondary nitroalkanes to ketones: a very mild Nef-type process

Abstract

Keywords

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