Causation of chronic lymphocytic leukemia - Insights from familial disease

Richard S. Houlston; Gabrielle Sellick; Martin Yuille; Estella Matutes; Daniel Catovsky

doi:10.1016/S0145-2126(03)00023-7

Causation of chronic lymphocytic leukemia - Insights from familial disease

Richard S. Houlston, Gabrielle Sellick, Martin Yuille, Estella Matutes, Daniel Catovsky

Research output: Contribution to journal › Article › peer-review

Abstract

In Western countries B-cell chronic lymphocytic leukemia (CLL) is the most common form of leukemia. Evidence from epidemiological studies and family studies strongly supports the notion that a subset of CLL involves inherited susceptibility. Identification of genes predisposing to CLL should be useful for diagnosis and treatment, as well as serving as a model for B-cell tumorigenesis in general. Here, we review the current status of knowledge about inherited susceptibility to CLL. © 2003 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	871-876
Number of pages	5
Journal	Leukemia Research
Volume	27
Issue number	10
DOIs	https://doi.org/10.1016/S0145-2126(03)00023-7
Publication status	Published - 1 Oct 2003

Keywords

Chronic lymphocytic leukemia
Inherited susceptibility

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0145-2126(03)00023-7

Cite this

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abstract = "In Western countries B-cell chronic lymphocytic leukemia (CLL) is the most common form of leukemia. Evidence from epidemiological studies and family studies strongly supports the notion that a subset of CLL involves inherited susceptibility. Identification of genes predisposing to CLL should be useful for diagnosis and treatment, as well as serving as a model for B-cell tumorigenesis in general. Here, we review the current status of knowledge about inherited susceptibility to CLL. {\textcopyright} 2003 Elsevier Science Ltd. All rights reserved.",

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AU - Houlston, Richard S.

AU - Sellick, Gabrielle

AU - Yuille, Martin

AU - Matutes, Estella

AU - Catovsky, Daniel

N1 - DA - 20030715IS - 0145-2126 (Print)LA - engPT - Journal ArticlePT - Research Support, Non-U.S. Gov'tPT - ReviewSB - IM

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N2 - In Western countries B-cell chronic lymphocytic leukemia (CLL) is the most common form of leukemia. Evidence from epidemiological studies and family studies strongly supports the notion that a subset of CLL involves inherited susceptibility. Identification of genes predisposing to CLL should be useful for diagnosis and treatment, as well as serving as a model for B-cell tumorigenesis in general. Here, we review the current status of knowledge about inherited susceptibility to CLL. © 2003 Elsevier Science Ltd. All rights reserved.

AB - In Western countries B-cell chronic lymphocytic leukemia (CLL) is the most common form of leukemia. Evidence from epidemiological studies and family studies strongly supports the notion that a subset of CLL involves inherited susceptibility. Identification of genes predisposing to CLL should be useful for diagnosis and treatment, as well as serving as a model for B-cell tumorigenesis in general. Here, we review the current status of knowledge about inherited susceptibility to CLL. © 2003 Elsevier Science Ltd. All rights reserved.

KW - Chronic lymphocytic leukemia

KW - Inherited susceptibility

U2 - 10.1016/S0145-2126(03)00023-7

DO - 10.1016/S0145-2126(03)00023-7

M3 - Article

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EP - 876

JO - Leukemia Research

JF - Leukemia Research

IS - 10

ER -

Causation of chronic lymphocytic leukemia - Insights from familial disease

Abstract

Keywords

UN SDGs

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