CD3ζ-based chimeric antigen receptors mediate T cell activation via cis- and trans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy

JS Bridgeman, K Ladell, VE Sheard, K Miners, RE Hawkins, DA Price, DE Gilham

    Research output: Contribution to journalArticlepeer-review

    Original languageEnglish
    Pages (from-to)258-267
    Number of pages9
    JournalClinical and experimental immunology
    Volume175
    Issue number2
    Early online date9 Oct 2013
    DOIs
    Publication statusPublished - Feb 2014

    Keywords

    • Gene therapy
    • T cells
    • Therapy/immunotherapy

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