Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

Bohdan Waszkowycz, Kate Smith, Alison Mcgonagle, Allan Jordan, Ben Acton, Emma Fairweather, Louise Griffiths, Niall M Hamilton, Nicola Hamilton, James R. Hitchin, Colin Hutton, Dominic I. James, Clifford D. Jones, Stuart Jones, Daniel Mould, Helen F. Small, Alexandra Stowell, Julie Tucker, Ian Waddell, Donald J. Ogilvie

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Pharmacology, Toxicology and Pharmaceutical Science