Centration of donor trephination in human corneal transplantation

Arun Brahma, Alan Ridgway, Andrew Tullo, Michael Boulton, Grenham Ireland, Stephen Bagley, Louise Carrington

    Research output: Contribution to journalArticlepeer-review


    Purpose: To develop and evaluate a new method to quantify centration of the trephined donor cornea relative to the limbus.

    Methods: After human donor corneas were trephined for penetrating keratoplasty, the remaining corneoscleral discs were stained and subjected to image analysis. The centration of the excised donor cornea relative to the limbus was calculated by measuring their centroids from the "captured" images.

    Results: Fifty-two corneoscleral discs were analyzed. The average deviation from the centre was 0.32 mm (SD, 0.18 mm). Neither surgeon nor the type of trephine significantly influenced the mean centroid deviation.

    Conclusion: We have developed and evaluated a method to quantify centration of human donor cornea. In a small series, decentration did not correlate significantly with either the surgeon or the trephine.
    Original languageEnglish
    Pages (from-to)325-328
    Number of pages4
    Issue number3
    Publication statusPublished - May 2000


    • Decentration
    • Penetrating keratoplasty
    • Trephination


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