Cerebral and peripheral oxygen saturation during red cell transfusion

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background. Changes in regional hemoglobin oxygen saturation occur in response to blood transfusion and can be measured by near infrared spectroscopy. Patients and methods. Cerebral (CsO2) and peripheral (PsO2) oxygen saturation were monitored with an INVOS 4100 near infrared spectroscopy oximeter in 29 patients undergoing 84 intraoperative blood transfusions during aortic or spinal surgery. Hemoglobin concentration was measured before and after transfusion. Mean arterial pressure, end tidal carbon dioxide tension, and arterial oxygen saturation were also monitored. Results. Mean arterial pressure, arterial oxygen saturation and end tidal carbon dioxide tension remained stable during transfusion, while CsO2 rose by a mean (95% CI) of 4.2 (3.2-5.2%; P = 0.001) and PsO2 rose by a mean (95% CI) of 1.6 (0.3-2.8%; P = 0.016). The rise in CsO2 correlated well with the rise in hemoglobin (r = 0.59, P <0.001) and with the volume transfused (r = 0.58, P <0.001). PsO2 correlated with the volume transfused (r = 0.35, P = 0.019) but not with hemoglobin concentration (r = 0.08, P = 0.47). Conclusions. Near infrared spectroscopy detected significant rises in tissue oxygenation in response to blood transfusion, particularly in the cerebral cortex. CsO2 may be developed into a blood loss monitor if further research confirms our findings. © 2003 Elsevier Science (USA).
    Original languageEnglish
    Pages (from-to)217-221
    Number of pages4
    JournalJournal of Surgical Research
    Volume110
    Issue number1
    DOIs
    Publication statusPublished - Mar 2003

    Keywords

    • Blood transfusion
    • Near infrared spectroscopy
    • Oxygen extraction

    Fingerprint

    Dive into the research topics of 'Cerebral and peripheral oxygen saturation during red cell transfusion'. Together they form a unique fingerprint.

    Cite this