Cerebral correlates of heart rate variations during a spontaneous panic attack in the fMRI scanner

Kai Spiegelhalder; Magdolna Hornyak; Simon David Kyle; Dominik Paul; Jens Blechert; Erich Seifritz; Jurgen Hennig; Ludger Tebartz van Elst; Dieter Riemann; Bernd Feige

doi:10.1080/13554790903066909

Cerebral correlates of heart rate variations during a spontaneous panic attack in the fMRI scanner

Kai Spiegelhalder, Magdolna Hornyak, Simon David Kyle, Dominik Paul, Jens Blechert, Erich Seifritz, Jurgen Hennig, Ludger Tebartz van Elst, Dieter Riemann, Bernd Feige

Research output: Contribution to journal › Article › peer-review

Abstract

We report the first published case study of a suddenly occurring panic attack in a patient with no prior history of panic disorder during combined functional magnetic resonance imaging (fMRI, 1.5 Tesla) and electrocardiogram (ECG) recording. The single case was a 46-year-old woman who developed a panic attack near the planned end of the fMRI acquisition session, which therefore had to be aborted. Correlational analysis of heart rate fluctuations and fMRI data revealed a significant negative association in the left middle temporal gyrus. Additionally, regions-of-interest (ROI) analyses indicated significant positive associations in the left amygdala, and trends towards significance in the right amygdala and left insula. © 2009 Psychology Press, an imprint of the Taylor & Francis Group, an Informa business.

Original language	English
Pages (from-to)	527-534
Number of pages	7
Journal	Neurocase
Volume	15
Issue number	6
DOIs	https://doi.org/10.1080/13554790903066909
Publication status	Published - Dec 2009

Keywords

Amygdala
ECG
fMRI
Insula
Panic attack

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10.1080/13554790903066909

Cite this

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abstract = "We report the first published case study of a suddenly occurring panic attack in a patient with no prior history of panic disorder during combined functional magnetic resonance imaging (fMRI, 1.5 Tesla) and electrocardiogram (ECG) recording. The single case was a 46-year-old woman who developed a panic attack near the planned end of the fMRI acquisition session, which therefore had to be aborted. Correlational analysis of heart rate fluctuations and fMRI data revealed a significant negative association in the left middle temporal gyrus. Additionally, regions-of-interest (ROI) analyses indicated significant positive associations in the left amygdala, and trends towards significance in the right amygdala and left insula. {\textcopyright} 2009 Psychology Press, an imprint of the Taylor & Francis Group, an Informa business.",

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AU - Spiegelhalder, Kai

AU - Hornyak, Magdolna

AU - Kyle, Simon David

AU - Paul, Dominik

AU - Blechert, Jens

AU - Seifritz, Erich

AU - Hennig, Jurgen

AU - van Elst, Ludger Tebartz

AU - Riemann, Dieter

AU - Feige, Bernd

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N2 - We report the first published case study of a suddenly occurring panic attack in a patient with no prior history of panic disorder during combined functional magnetic resonance imaging (fMRI, 1.5 Tesla) and electrocardiogram (ECG) recording. The single case was a 46-year-old woman who developed a panic attack near the planned end of the fMRI acquisition session, which therefore had to be aborted. Correlational analysis of heart rate fluctuations and fMRI data revealed a significant negative association in the left middle temporal gyrus. Additionally, regions-of-interest (ROI) analyses indicated significant positive associations in the left amygdala, and trends towards significance in the right amygdala and left insula. © 2009 Psychology Press, an imprint of the Taylor & Francis Group, an Informa business.

AB - We report the first published case study of a suddenly occurring panic attack in a patient with no prior history of panic disorder during combined functional magnetic resonance imaging (fMRI, 1.5 Tesla) and electrocardiogram (ECG) recording. The single case was a 46-year-old woman who developed a panic attack near the planned end of the fMRI acquisition session, which therefore had to be aborted. Correlational analysis of heart rate fluctuations and fMRI data revealed a significant negative association in the left middle temporal gyrus. Additionally, regions-of-interest (ROI) analyses indicated significant positive associations in the left amygdala, and trends towards significance in the right amygdala and left insula. © 2009 Psychology Press, an imprint of the Taylor & Francis Group, an Informa business.

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KW - ECG

KW - fMRI

KW - Insula

KW - Panic attack

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Cerebral correlates of heart rate variations during a spontaneous panic attack in the fMRI scanner

Abstract

Keywords

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