Cerebroplacental ratio-based management versus care as usual in non-small-for-gestational-age fetuses at term with maternal perceived reduced fetal movements (CEPRA): a multicentre, cluster-randomised controlled trial

Laura A Lens; Selina Posthuma; Stefanie E Damhuis; Renée J Burger; Henk Groen; Ruben G Duijnhoven; Sailesh Kumar; Alexander E P Heazell; Asma Khalil; Wessel Ganzevoort; Sanne J Gordijn; Salwan Al-Nasiry; Eline S.A. van den Akker; Joost Akkermans; Anita G.M. Nijkamp-Bettman; Froukje de Boer; Marjon A. de Boer; Janine Boon; Liv M. Freeman; Roel de Heus; Jesrine Hong; Anjoke J.M. Huisjes; Elisabeth M.W. Kooi; Joep C. Kortekaas; Simone Lunshof; Etelka Moll; Leonard P. Morssink; Janna M. Munster; Hedwig P. van de Nieuwenhof; Mariëlle G. van Pampus; Jelle M. Schaaf; Marieke Sueters; Floortje Vlemmix; Sabina de Weerd

doi:10.1016/j.lanogw.2025.100002

Cerebroplacental ratio-based management versus care as usual in non-small-for-gestational-age fetuses at term with maternal perceived reduced fetal movements (CEPRA): a multicentre, cluster-randomised controlled trial

Laura A Lens, Selina Posthuma, Stefanie E Damhuis, Renée J Burger, Henk Groen, Ruben G Duijnhoven, Sailesh Kumar, Alexander E P Heazell, Asma Khalil, Wessel Ganzevoort, Sanne J Gordijn, Salwan Al-Nasiry, Eline S.A. van den Akker, Joost Akkermans, Anita G.M. Nijkamp-Bettman, Froukje de Boer, Marjon A. de Boer, Janine Boon, Liv M. Freeman, Roel de HeusJesrine Hong, Anjoke J.M. Huisjes, Elisabeth M.W. Kooi, Joep C. Kortekaas, Simone Lunshof, Etelka Moll, Leonard P. Morssink, Janna M. Munster, Hedwig P. van de Nieuwenhof, Mariëlle G. van Pampus, Jelle M. Schaaf, Marieke Sueters, Floortje Vlemmix, Sabina de Weerd

Division of Developmental Biology & Medicine (L5)

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	100002
Journal	The Lancet Obstetrics, Gynaecology, & Women's Health
DOIs	https://doi.org/10.1016/j.lanogw.2025.100002
Publication status	Published - 10 Jul 2025

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10.1016/j.lanogw.2025.100002

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Lens, L. A., Posthuma, S., Damhuis, S. E., Burger, R. J., Groen, H., Duijnhoven, R. G., Kumar, S., Heazell, A. E. P., Khalil, A., Ganzevoort, W., Gordijn, S. J., Al-Nasiry, S., van den Akker, E. S. A., Akkermans, J., G.M. Nijkamp-Bettman, A., de Boer, F., de Boer, M. A., Boon, J., Freeman, L. M., ... de Weerd, S. (2025). Cerebroplacental ratio-based management versus care as usual in non-small-for-gestational-age fetuses at term with maternal perceived reduced fetal movements (CEPRA): a multicentre, cluster-randomised controlled trial. The Lancet Obstetrics, Gynaecology, & Women's Health, Article 100002. https://doi.org/10.1016/j.lanogw.2025.100002

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title = "Cerebroplacental ratio-based management versus care as usual in non-small-for-gestational-age fetuses at term with maternal perceived reduced fetal movements (CEPRA): a multicentre, cluster-randomised controlled trial",

author = "Lens, \{Laura A\} and Selina Posthuma and Damhuis, \{Stefanie E\} and Burger, \{Ren{\'e}e J\} and Henk Groen and Duijnhoven, \{Ruben G\} and Sailesh Kumar and Heazell, \{Alexander E P\} and Asma Khalil and Wessel Ganzevoort and Gordijn, \{Sanne J\} and Salwan Al-Nasiry and \{van den Akker\}, \{Eline S.A.\} and Joost Akkermans and \{G.M. Nijkamp-Bettman\}, Anita and \{de Boer\}, Froukje and \{de Boer\}, \{Marjon A.\} and Janine Boon and Freeman, \{Liv M.\} and \{de Heus\}, Roel and Jesrine Hong and \{J.M. Huisjes\}, Anjoke and Kooi, \{Elisabeth M.W.\} and Kortekaas, \{Joep C.\} and Simone Lunshof and Etelka Moll and Morssink, \{Leonard P.\} and Munster, \{Janna M.\} and \{van de Nieuwenhof\}, \{Hedwig P.\} and \{van Pampus\}, \{Mari{\"e}lle G.\} and Schaaf, \{Jelle M.\} and Marieke Sueters and Floortje Vlemmix and \{de Weerd\}, Sabina",

year = "2025",

month = jul,

day = "10",

doi = "10.1016/j.lanogw.2025.100002",

language = "English",

journal = "The Lancet Obstetrics, Gynaecology, \& Women's Health",

issn = "3050-5038",

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Lens, LA, Posthuma, S, Damhuis, SE, Burger, RJ, Groen, H, Duijnhoven, RG, Kumar, S, Heazell, AEP, Khalil, A, Ganzevoort, W, Gordijn, SJ, Al-Nasiry, S, van den Akker, ESA, Akkermans, J, G.M. Nijkamp-Bettman, A, de Boer, F, de Boer, MA, Boon, J, Freeman, LM, de Heus, R, Hong, J, J.M. Huisjes, A, Kooi, EMW, Kortekaas, JC, Lunshof, S, Moll, E, Morssink, LP, Munster, JM, van de Nieuwenhof, HP, van Pampus, MG, Schaaf, JM, Sueters, M, Vlemmix, F & de Weerd, S 2025, 'Cerebroplacental ratio-based management versus care as usual in non-small-for-gestational-age fetuses at term with maternal perceived reduced fetal movements (CEPRA): a multicentre, cluster-randomised controlled trial', The Lancet Obstetrics, Gynaecology, & Women's Health. https://doi.org/10.1016/j.lanogw.2025.100002

Cerebroplacental ratio-based management versus care as usual in non-small-for-gestational-age fetuses at term with maternal perceived reduced fetal movements (CEPRA): a multicentre, cluster-randomised controlled trial. / Lens, Laura A; Posthuma, Selina; Damhuis, Stefanie E et al.
In: The Lancet Obstetrics, Gynaecology, & Women's Health, 10.07.2025.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Cerebroplacental ratio-based management versus care as usual in non-small-for-gestational-age fetuses at term with maternal perceived reduced fetal movements (CEPRA): a multicentre, cluster-randomised controlled trial

AU - Lens, Laura A

AU - Posthuma, Selina

AU - Damhuis, Stefanie E

AU - Burger, Renée J

AU - Groen, Henk

AU - Duijnhoven, Ruben G

AU - Kumar, Sailesh

AU - Heazell, Alexander E P

AU - Khalil, Asma

AU - Ganzevoort, Wessel

AU - Gordijn, Sanne J

AU - Al-Nasiry, Salwan

AU - van den Akker, Eline S.A.

AU - Akkermans, Joost

AU - G.M. Nijkamp-Bettman, Anita

AU - de Boer, Froukje

AU - de Boer, Marjon A.

AU - Boon, Janine

AU - Freeman, Liv M.

AU - de Heus, Roel

AU - Hong, Jesrine

AU - J.M. Huisjes, Anjoke

AU - Kooi, Elisabeth M.W.

AU - Kortekaas, Joep C.

AU - Lunshof, Simone

AU - Moll, Etelka

AU - Morssink, Leonard P.

AU - Munster, Janna M.

AU - van de Nieuwenhof, Hedwig P.

AU - van Pampus, Mariëlle G.

AU - Schaaf, Jelle M.

AU - Sueters, Marieke

AU - Vlemmix, Floortje

AU - de Weerd, Sabina

PY - 2025/7/10

Y1 - 2025/7/10

U2 - 10.1016/j.lanogw.2025.100002

DO - 10.1016/j.lanogw.2025.100002

M3 - Article

SN - 3050-5038

JO - The Lancet Obstetrics, Gynaecology, & Women's Health

JF - The Lancet Obstetrics, Gynaecology, & Women's Health

M1 - 100002

ER -

Lens LA, Posthuma S, Damhuis SE, Burger RJ, Groen H, Duijnhoven RG et al. Cerebroplacental ratio-based management versus care as usual in non-small-for-gestational-age fetuses at term with maternal perceived reduced fetal movements (CEPRA): a multicentre, cluster-randomised controlled trial. The Lancet Obstetrics, Gynaecology, & Women's Health. 2025 Jul 10;100002. doi: 10.1016/j.lanogw.2025.100002